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ESP Timelines

Comparative Timelines

The ESP Timeline (one of the site's most popular features) has been completely updated to allow the user to select (using the timeline controls above each column) different topics for the left and right sides of the display.

Select:

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Dates

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1470

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1471

After having secured much of what today is central and northern Peru, the Inca have expanded their empire into Ecuador. With a new king, Tupac Inca, they begin to expand southward into Chile, Bolivia and Argentina.

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1472

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1473

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1474

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1475

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1476

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1477

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1478

A conspiracy, that includes the Archbishop of Pisa and has the support of Pope Sixtus IV, leads to an attack on the Medici while they are in church. The Archbishop and several others are hanged. Pope Sixtus puts Florence under the interdict and excommunicates the Medici leader of Florence, Lorenzo de Medici. The pope forms a military alliance with the King of Naples, and Lorenzo's diplomacy prevents an attack.

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1479

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1480

Ferdinand and Isabella of Spain employ the Spanish Inquisition to investigate whether converted Jews are secretly clinging to Judaism.

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1481

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1482

Portuguese have founded new trading settlements on Africa's "Gold Coast." They are trading ironware, firearms, textiles and food for gold, ivory, food and slaves.

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1483

Edward IV of England has died. His son succeeds him as Edward V, and he is murdered. The Duke of Gloucester, the youngest brother of Edward IV, usurps the throne and is crowned Richard III.

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1484

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1485

Henry Tudor, a relative of the Lancaster family, defeats Richard III at the Battle of Bosworth. The Tudor family takes power and is crowned Henry VII.

Henry VII marries Elizabeth of York, uniting the Lancaster and York families. The War of Roses is over.

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1486

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1487

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1488

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1489

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1490

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1491

King Charles VIII of France invades Brittany and forces 14-year-old Ann of Brittany to marry him, adding Brittany to French territory.

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1492

Spain's monarchs, Ferdinand and Isabella, do their part in a war against Islam — they annex Granada. Also they give Jews three months to convert to Christianity if they are to avoid banishment from the country. And the voyage that the monarchy is paying for, led by Christopher Columbus, sets sail for China by going westward.

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1493

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1494

Piero de Medici has ruled since the death of his father, Lorenzo, in 1492. He makes peace with the French, who have invaded Tuscany (in which Florence is located). A political rising drives him into exile. Florence is in anarchy. A Dominican priest, Savonarola, is anti-Renaissance. He is opposed to popular music, art and other worldliness.

image The Treaty of Tordesillas, signed in Tordesillas, Spain, on 7 June 1494, and ratified in Setúbal, Portugal, divided the newly discovered lands outside Europe between the Kingdom of Portugal and the Crown of Castile, along a meridian 370 leagues west of the Cape Verde islands, off the west coast of Africa. That line of demarcation was about halfway between Cape Verde (already Portuguese) and the islands visited by Christopher Columbus on his first voyage (claimed for Castile and León), named in the treaty as Cipangu and Antillia (Cuba and Hispaniola). The lands to the east would belong to Portugal and the lands to the west to Castile, modifying an earlier bull by Pope Alexander VI. The treaty was signed by Spain on 2 July 1494, and by Portugal on 5 September 1494. The other side of the world was divided a few decades later by the Treaty of Zaragoza, signed on 22 April 1529, which specified the antimeridian to the line of demarcation specified in the Treaty of Tordesillas. Portugal and Spain largely respected the treaties, while the indigenous peoples of the Americas did not acknowledge them.

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1495

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1496

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1497

Boys working under Savonarola collect from homes things associated with moral laxity: mirrors, cosmetics, pictures, books, fine dresses, the works of immoral poets. Savonarola has these burned. Renaissance art work is lost. Pope Alexander VI excommunicates Savonarola.

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1498

Savonarola is hanged. An enraged crowd burns Savonarola at the same spot where he ordered his bonfire.

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1499

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1500

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1501

African Slaves in the New World Spanish settlers bring slaves from Africa to Santo Domingo (now the capital of the Dominican Republic).

image Ismail I, the founder and first shah of Safavid Iran, ruled from 1501 until his death in 1524. His reign is often considered the beginning of modern Iranian history, as well as one of the gunpowder empires. The rule of Ismail I is one of the most vital in the history of Iran. Before his accession in 1501, Iran, since its Islamic conquest eight-and-a-half centuries earlier, had not existed as a unified country under native Iranian rule. The dynasty founded by Ismail I would rule for over two centuries, being one of the greatest Iranian empires and at its height being amongst the most powerful empires of its time, ruling all of present-day Iran, the Republic of Azerbaijan, Armenia, most of Georgia, the North Caucasus, and Iraq, as well as parts of modern-day Turkey, Syria, Pakistan, Afghanistan, Uzbekistan, and Turkmenistan.

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1502

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1503

image At the Battle of Cerignola Spanish forces defeat the French, considered the first battle in history won by gunpowder small arms.

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1504

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1505

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1506

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1507

image Martin Luther ordained to the priesthood. Luther was the seminal figure of the Protestant Reformation. He is widely regarded as one of the most influential figures in Western and Christian history. He came to reject several teachings and practices of the Roman Catholic Church; in particular, he disputed the view on indulgences. Luther attempted to resolve these differences amicably, first proposing an academic discussion of the practice and efficacy of indulgences in Ninety-five Theses, which he authored in 1517. In 1520, Pope Leo X demanded that Luther renounce all of his writings, and when Luther refused to do so, excommunicated him in January 1521. Later that year, Holy Roman Emperor Charles V condemned Luther as an outlaw at the Diet of Worms. When Luther died in 1546, Pope Leo X's excommunication was still in effect. Luther taught that salvation and, consequently, eternal life are not earned by good deeds; rather, they are received only as the free gift of God's grace through the believer's faith in Jesus Christ, who is the sole redeemer from sin. Luther's theology challenged the authority and office of the pope by teaching that the Bible is the only source of divinely revealed knowledge, and opposed sacerdotalism by considering all baptized Christians to be a holy priesthood. Attempts by the Catholic Church to suppress the new protestant movement led to more than 200 years of wars — the European wars of religion.

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1508

image Maximilian I becomes Holy Roman Emperor, a role he held until his death in 1519. He was never crowned by the Pope, as the journey to Rome was blocked by the Venetians. He proclaimed himself elected emperor in 1508 (Pope Julius II later recognized this) at Trent, thus breaking the long tradition of requiring a papal coronation for the adoption of the Imperial title. Maximilian was the only surviving son of Frederick III, Holy Roman Emperor, and Eleanor of Portugal. Since his coronation as King of the Romans in 1486, he ran a double government, or Doppelregierung (with a separate court), with his father until Frederick's death in 1493. Maximilian expanded the influence of the House of Habsburg through war and his marriage in 1477 to Mary of Burgundy, the ruler of the Burgundian State, heiress of Charles the Bold, though he also lost his family's original lands in today's Switzerland to the Swiss Confederacy. Through the marriage of his son Philip the Handsome to eventual queen Joanna of Castile in 1496, Maximilian helped to establish the Habsburg dynasty in Spain, which allowed his grandson Charles to hold the thrones of both Castile and Aragon.

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1509

image Henry VIII becomes King of England. Henry is known for his six marriages and his efforts to have his first marriage (to Catherine of Aragon) annulled. His disagreement with Pope Clement VII about such an annulment led Henry to initiate the English Reformation, separating the Church of England from papal authority. He appointed himself Supreme Head of the Church of England and dissolved convents and monasteries, for which he was excommunicated by the pope. Henry brought radical changes to the Constitution of England, expanding royal power and ushering in the theory of the divine right of kings in opposition to papal supremacy. He frequently used charges of treason and heresy to quell dissent, and those accused were often executed without a formal trial using bills of attainder. He achieved many of his political aims through his chief ministers, some of whom were banished or executed when they fell out of his favor. Thomas Wolsey, Thomas More, Thomas Cromwell, and Thomas Cranmer all figured prominently in his administration.

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1510

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1511

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1512

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1513

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1514

Raphael's friend, courtier Giovanbattista Branconio dell'Aquila, becomes the personal keeper of Hanno, the white elephant brought to Rome in 1514, as a gift by King Manuel I of Portugal to Pope Leo X (born Giovanni de' Medici) at his coronation.

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1515

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1516

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1517

image Martin Luther publishes his Ninety-five Theses or Disputation on the Power and Efficacy of Indulgences, a list of propositions for an academic disputation. This work is retrospectively considered to have launched the Protestant Reformation and the birth of Protestantism, despite various proto-Protestant groups having existed previously. It detailed Luther's opposition to what he saw as the Roman Catholic Church's abuse and corruption by Catholic clergy, who were selling plenary indulgences, which were certificates supposed to reduce the temporal punishment in purgatory for sins committed by the purchasers or their loved ones.

Ottoman Turks defeat the Mamluks of Egypt and take control of Egypt and the Arabian Peninsula.

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1518

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1519

Horses are brought to the New World by Hernán Cortéz.

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1520

Suleiman I, also known as Suleiman the Magnificent, became Sultan in 1520 and led the Ottoman Empire to its greatest height. He expanded the empire's territory, reformed its legal system, and oversaw a cultural and artistic flourishing known as the Ottoman Renaissance.

Beginning of anabaptist movement in Germany under Thomas Münzer.

Pope Leo X excommunicates Martin Luther.

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1521

image Pope Leo X confers title Defender of the Faith on King Henry VIII for his Assertio septem sacramentorum against Luther.

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1522

Slave Revolt: the Caribbean Slaves rebel on the Caribbean island of Hispaniola, which now comprises Haiti and the Dominican Republic.

image Adrian of Utrecht, Regent of Spain, elected Pope Adrian VI, the last non-Italian Pope for some time.

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1523

image Pope Adrian VI dies, Giulio de' Medici becomes Pope Clement VII. Deemed the most unfortunate of the popes, Clement VII's reign was marked by a rapid succession of political, military, and religious struggles — many long in the making — which had far-reaching consequences for Christianity and world politics. Elected in 1524 at the end of the Italian Renaissance, Clement came to the papacy with a high reputation as a statesman. He had served with distinction as chief advisor to Pope Leo X (1513–1521, his cousin), Pope Adrian VI (1522–1523), and commendably as gran maestro of Florence (1519–1523). Assuming leadership at a time of crisis, with the Protestant Reformation spreading, the Church nearing bankruptcy, and large foreign armies invading Italy, Clement initially tried to unite Christendom by making peace among the many Christian leaders then at odds. He later attempted to liberate Italy from foreign occupation, believing that it threatened the Church's freedom. The complex political situation of the 1520s thwarted Clement's efforts.

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1524

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1525

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1526

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1527

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1528

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1529

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1530

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1531

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1532

image Francisco Pizarro leads the Spanish conquest of the Inca Empire.

Sugarcane is first grown in Brazil.

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1533

image Anne Boleyn becomes Queen of England. Anne was the daughter of Thomas Boleyn (later Earl of Wiltshire), and his wife, Elizabeth Howard, and was educated in the Netherlands and France. Anne returned to England in early 1522, to marry her cousin James Butler, 9th Earl of Ormond; the marriage plans were broken off, and instead, she secured a post at court as maid of honor to Henry VIII's wife, Catherine of Aragon. Early in 1523, Anne was secretly betrothed to Henry Percy, son of Henry Percy, 5th Earl of Northumberland, but the betrothal was broken off when the Earl refused to support it. Cardinal Thomas Wolsey refused the match in January 1524. In February or March 1526, Henry VIII began his pursuit of Anne. She resisted his attempts to seduce her, refusing to become his mistress, as her sister Mary had previously been. Henry focused on annulling his marriage to Catherine, so he would be free to marry Anne. After Wolsey failed to obtain an annulment from Pope Clement VII, it became clear the marriage would not be annulled by the Catholic Church. As a result, Henry and his advisers, such as Thomas Cromwell, began breaking the Church's power in England and closing the monasteries. Henry and Anne formally married on 25 January 1533, after a secret wedding on 14 November 1532.

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1534

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1535

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1536

image Anne Boleyn is beheaded for adultery and treason.

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1537

image William Tyndale's partial translation of the Bible into English is published, which would eventually be incorporated into the King James Bible.

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1538

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1539

Spain annexes Cuba.

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1540

Hernando de Alarcón sets sail to explore the Baja California peninsula; on September 26 he enters the Colorado River.

The Society of Jesus, or the Jesuits, is founded by Ignatius of Loyola and six companions with the approval of Pope Paul III.

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1541

The western headwaters of the Amazon River are encountered and explored by Francisco de Orellana.

Spanish explorer Hernando de Soto reaches the Mississippi River, naming it Rio de Espiritu Santo.

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1542

Juan Rodríguez Cabrillo explores the coast of California.

Pope Paul III establishes the Inquisition in Rome.

War resumes between Francis I of France and Emperor Charles V. This time Henry VIII is allied with the Emperor, while James V of Scotland and Sultan Suleiman I are allied with the French.

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1543

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1544

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1545

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1546

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1547

image Edward VI becomes King of England and Ireland on 28 January and is crowned on 20 February at the age of 9. The son of Henry VIII and Jane Seymour, Edward was England's first monarch to be raised as a Protestant. During his reign, the realm was governed by a Regency Council because he never reached his majority.

image Grand Prince Ivan the Terrible is crowned tsar of (All)Russia, thenceforth becoming the first Russian tsar.

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1548

Battle of Uedahara: Firearms are used for the first time on the battlefield in Japan.

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1549

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1550

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1551

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1552

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1553

image Mary Tudor becomes the first queen regnant of England and restores the Church of England under Papal authority.

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1554

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1555

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1556

Pomponio Algerio, 25-year-old radical theologian, is executed by boiling in oil as part of the Roman inquisition. After refusing to conform to Church doctrine, he was sentenced to prison and asked to reconsider his Lutheran beliefs. After a year behind bars, he still refused to reconsider. Because Venetian authorities would not consent to an execution, Pope Paul IV sent officials to extradite Pomponio to Rome. In Rome, on 21 August 1555, a monk from the brotherhood of St John the Beheaded visited Pomponio in his cell urging him to repent. If he repented, he would be strangled before burning. The 24-year-old student refused. One year later, on 22 August 1556, he was executed by civil authorities in the Piazza Navona, Rome. Maintaining his composure while he was boiled in oil, he stayed alive for 15 minutes before dying.

The Shaanxi earthquake in China, during the Ming Dynasty, is history's deadliest known earthquake, killing approximately 830,000 people.

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1557

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1558

image Elizabeth Tudor becomes Queen Elizabeth I at age 25. Sometimes called The Virgin Queen, Gloriana or Good Queen Bess, the childless Elizabeth was the last monarch of the Tudor dynasty. Elizabeth was the daughter of Henry VIII and Anne Boleyn, his second wife, who was executed two-and-a-half years after Elizabeth's birth. Anne's marriage to Henry VIII was annulled, and Elizabeth was declared illegitimate. Elizabeth's reign is known as the Elizabethan era. The period is famous for the flourishing of English drama, led by playwrights such as William Shakespeare and Christopher Marlowe, and for the seafaring prowess of English adventurers such as Francis Drake.

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1559

Led by Don Tristán de Luna y Arellano, a Spanish missionary colony of 1500 men on thirteen ships arrives from Vera Cruz at Pensacola Bay, founding the first European settlement on the mainland United States. On September 19, the colony is decimated by a hurricane.

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1560

image By winning the Battle of Okehazama, Oda Nobunaga becomes one of the pre-eminent warlords of Japan.

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1561

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1562

Britain Joins Slave Trade. John Hawkins, the first Briton to take part in the slave trade, makes a huge profit hauling human cargo from Africa to Hispaniola.

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1563

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1564

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1565

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1566

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1567

image Mary, Queen of Scots, is imprisoned by Elizabeth I. Mary, the only surviving legitimate child of James V of Scotland, was six days old when her father died and she acceded to the throne. Mary had previously claimed Elizabeth's throne as her own and was considered the legitimate sovereign of England by many English Catholics, including participants in a rebellion known as the Rising of the North. Perceiving her as a threat, Elizabeth had her confined in various castles and manor houses in the interior of England. After eighteen and a half years in custody, Mary was found guilty of plotting to assassinate Elizabeth in 1586. She was beheaded the following year.

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1568

The Transylvanian Diet, under the patronage of the prince John Sigismund Zápolya, the former King of Hungary, inspired by the teachings of Ferenc Dávid, the founder of the Unitarian Church of Transylvania, promulgates the Edict of Torda, the first law of Freedom of religion and of conscience in the World.

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1569

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1570

image Pope Pius V issues Regnans in Excelsis, a papal bull excommunicating all who obeyed Elizabeth I and calling on all Roman Catholics to rebel against her.

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1571

The Ottoman Empire suffered a major defeat at the Battle of Lepanto, a naval battle fought against a coalition of Christian states led by the Holy League. Despite the loss, the Ottoman navy remained a dominant force in the Mediterranean.

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1572

image The last Inca leader Tupak Amaru apprehended by Spanish conquistadores at Vilcabamba, Peru, and executed in Cuzco.

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1573

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1574

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1575

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1576

English navigator Martin Frobisher sights Greenland.

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1577

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1578

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1579

Francis Drake, during his circumnavigation of the world, lands in what is now California, which he claims for Queen Elizabeth I of England as Nova Albion.

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1580

Francis Drake in the Golden Hind sails into Plymouth having completed the second circumnavigation of the world, westabout, begun in 1577.

Spain unifies with Portugal under Philip II. The struggle for the throne of Portugal ends the Portuguese Empire. The Spanish and Portuguese crowns are united for 60 years, i.e. until 1640.

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1581

Slaves in Florida Spanish residents in St. Augustine, the first permanent settlement in Florida, import African slaves.

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1582

image Pope Gregory XIII issues papal bull Inter Gravissimas, thereby establishing the The Gregorian Calendar. The last day of the Julian calendar was Thursday, 4 October 1582 and this was followed by the first day of the Gregorian calendar, Friday, 15 October 1582.

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1583

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1584

Walter Raleigh sends Philip Amadas and Arthur Barlowe to explore the Outer Banks of Virginia (now North Carolina), with a view to establishing an English colony; they locate Roanoke Island.

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1585

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1586

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1587

Mary, Queen of Scots, is executed by Elizabeth I.

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1588

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1589

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1590

At the Siege of Odawara the Go-Hojo clan surrendered to Toyotomi Hideyoshi, unifying Japan.

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1591

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1592

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1593

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1594

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1595

A Spanish expedition led by lvaro de Menda a de Neira makes the first European landing in Polynesia, on the Marquesas Islands.

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1596

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1597

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1598

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1599

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1600

image Battle of Sekigahara in Japan. End of the Warring States period and beginning of the Edo period.

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1601

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1602

The Dutch East India Company (VOC) is established by merging competing Dutch trading companies.[4] Its success contributes to the Dutch Golden Age.

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1603

image Tokugawa Ieyasu takes the title of Shogun, establishing the Tokugawa Shogunate. This begins the Edo period, which will last until 1869.

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1604

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1605

Johann Carolus of Germany publishes the 'Relation', the first newspaper.

Tokugawa Ieyasu passes the title of Shogun to his son, Tokugawa Hidetada, and "retires" to Sunpu.

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1606

Captain Willem Janszoon and his crew aboard the Dutch East India Company ship Duyfken becomes the first recorded Europeans to sight and make landfall in Australia.

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1607

Jamestown, Virginia, is settled as what would become the first permanent English colony in North America.

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1608

Quebec City founded by Samuel de Champlain in New France (present-day Canada).

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1609

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1610

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1611

image King James Bible is first published. The KJV is an English translation of the Christian Bible for the Church of England begun in 1604 and completed in 1611. The books of the King James Version include the 39 books of the Old Testament, an intertestamental section containing 14 books of the Apocrypha (most of which correspond to books in the Vulgate Deuterocanon adhered to by Roman Catholics), and the 27 books of the New Testament. It was first printed by the King's Printer Robert Barker and was the third translation into English approved by the English Church authorities.

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1612

The first commercial tobacco crop is raised in Jamestown, Virginia.

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1613

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1614

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1615

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1616

Death of retired Shogun Tokugawa Ieyasu.

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1617

image Nikko Tosho-gu Shrine, dedicated to Tokugawa Ieyasu, the founder of the Tokugawa shogunate, is built. Ieyasu is enshrined there, where his remains are also entombed. During the Edo period, the Tokugawa shogunate carried out stately processions from Edo to the Nikko Tosho-gu. The shrine's annual spring and autumn festivals reenact these occasions, and are known as processions of a thousand warriors. Five structures at Nikko Tosho-gu are categorized as National Treasures of Japan, and three more as Important Cultural Properties. The stable of the shrine's sacred horses bears a carving of the three wise monkeys, who hear, speak and see no evil, a traditional symbol in Chinese and Japanese culture.

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1618

Beginning of the Thirty Years War..

The Manchus start invading China. Their conquest eventually topples the Ming Dynasty.

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1619

Twenty slaves in Virginia Africans brought to Jamestown are the first slaves imported into Britain's North American colonies. Like indentured servants, they were probably freed after a fixed period of service.

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1620

The Mayflower arrives at Cape Cod bearing Brownist Pilgrims.

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1621

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1622

image Jamestown massacre: Algonquian natives kill 347 English settlers outside Jamestown, Virginia (one-third of the colony's population) and burn the Henricus settlement.

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1623

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1624

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1625

English settlers occupy the islands of Barbados and St. Kitts.

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1626

image Pieter Jansz Schaghen writes to the States General of the Dutch Republic announcing the purchase of Manhattan from the Native Americans.

The Dutch West India Company imports 11 black male slaves into the New Netherlands.

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1627

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1628

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1629

English troops capture Qu bec.

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1630

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1631

Mount Vesuvius erupts.

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1632

Charles I of England grants a charter to Cecilius Calvert, second Lord Baltimore, for colony in Maryland

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1633

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1634

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1635

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1636

Harvard College is established.

Colonial North America's slave trade begins when the first American slave carrier, Desire, is built and launched in Massachusetts.

Harvard University is founded in Cambridge, Massachusetts.

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1637

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1638

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1639

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1640

John Punch, a runaway black servant, is sentenced to servitude for life. His two white companions are given extended terms of servitude. Punch is the first documented slave for life.

New Netherlands law forbids residents from harboring or feeding runaway slaves.

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1641

Massachusetts is the first colony to legalize slavery.

The D'Angola marriage is the first recorded marriage between blacks in New Amsterdam.

The Tokugawa Shogunate institutes Sakoku — foreigners are expelled and no one is allowed to enter or leave Japan.

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1642

The city of Montr al is founded in what will become Canada.

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1643

The New England Confederation of Plymouth, Massachusetts, Connecticut, and New Haven adopts a fugitive slave law.

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1644

Manchu dynasty established in China; end of the Ming line.

The Manchu conquer China ending the Ming Dynasty. The subsequent Qing Dynasty rules until 1912.

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1645

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1646

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1647

Peter Stuyvesant appointed governor of New Amsterdam.

George Fox founds the Society of Friends, or Quakers, in England.

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1648

image The Peace of Westphalia ends the Thirty Years' War and the Eighty Years' War and marks the ends of Spain and the Holy Roman Empire as major European powers.

The Peace of Westphalia brings an end to the Thiry Years War.

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1649

image King Charles I is executed for High treason, the first and only English king to be subjected to legal proceedings in a High Court of Justice and put to death.

George Fox, the founder of the Society of Friends, is imprisoned at Nottingham.

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1650

Connecticut legalizes slavery.

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1651

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1652

Massachusetts requires all black and Indian servants to receive military training.

Rhode Island passes laws restricting slavery and forbidding enslavement for more than 10 years.

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1653

Oliver Cromwell dissolves the Rump Parliament and replaces it with the Nominated Assembly (also called the Assembly of Saints or Barebones Parliament.) After three months, the Nominated Assembly passes a motion to dissolve itself and Cromwell establishes the Protectorate.

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1654

A Virginia court grants blacks the right to hold slaves.

Scotland incorporated with the English Commonwealth.

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1655

The island of Jamaica is captured from the Spaniards by the English.

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1656

The first persecution of Quakers occurs in Massachusetts.

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1657

Virginia passes a fugitive slave law.

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1658

Cromwell dies and his son Richard becomes Lord Protector.

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1659

Richard Cromwell is pressured into dissolving the Protectorate; the Rump Parliament is restored.

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1660

Charles II, King of England, orders the Council of Foreign Plantations to devise strategies for converting slaves and servants to Christianity.

End of Puritan rule in England; restoration of the Stuarts.

The Commonwealth of England ends and the monarchy is brought back during the English Restoration.

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1661

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1662

Hereditary slavery is established, when Virginia law decrees that children of black mothers shall be bond or free according to the condition of the mother.

Massachusetts reverses a ruling dating back to 1652, which allowed blacks to train in arms. New York, Connecticut, and New Hampshire pass similar laws restricting the bearing of arms.

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1663

Charles II, King of England, gives the Carolinas to proprietors. Until the 1680s, most settlers in the region are small landowners from Barbados.

In Gloucester County, Virginia the first documented slave rebellion in the colonies takes place.

Maryland legalizes slavery.

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1664

Maryland is the first colony to take legal action against marriages between white women and black men.

New York and New Jersey legalize slavery.

The State of Maryland mandates lifelong servitude for all black slaves. New York, New Jersey, the Carolinas, and Virginia all pass similar laws.

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1665

Great Plague occurs in London.

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1666

Maryland passes a fugitive slave law.

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1667

Virginia declares that Christian baptism will not alter a person's status as a slave.

Treaty of Breda; peace established among England, Holland, France, Denmark.

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1668

The Mission of Sault Ste. Marie, in what will become Michigan, is founded by Father Marquette.

New Jersey passes a fugitive slave law.

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1669

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1670

The Hudson Bay Company is incorporated.

The State of Virginia prohibits free blacks and Indians from keeping Christian (i.e. white) servants.

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1671

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1672

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1673

The Mississippi River is discovered.

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1674

New York declares that blacks who convert to Christianity after their enslavement will not be freed.

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1675

King Philip's War (sometimes called the First Indian War, Metacom's War, Metacomet's War, or Metacom's Rebellion) begins in New England. The war was an armed conflict between American Indian inhabitants of present-day New England and English colonists and their Indian allies in 1675 78. The war is named for Metacomet, the Wampanoag chief who adopted the English name Philip due to the friendly relations between his father and the Mayflower Pilgrims. The war continued in the most northern reaches of New England until the signing of the Treaty of Casco Bay in April 1678. The war was the single greatest calamity to occur in seventeenth century Puritan New England and is considered by many to be the deadliest war in the history of European settlement in North America in proportion to the population. In the space of little more than a year, twelve of the region's towns were destroyed and many more damaged, the colony's economy was all but ruined, and its population was decimated, losing one-tenth of all men available for military service. More than half of New England's towns were attacked by Indians. By early July, over 400 had surrendered to the colonists, and Metacomet took refuge in the Assowamset Swamp below Providence, close to where the war had started. The colonists formed raiding parties of militia and Indians. They were allowed to keep the possessions of warring Indians and received a bounty on all captives. Metacomet was killed by one of these teams when he was tracked down by Captain Benjamin Church and Captain Josiah Standish of the Plymouth Colony militia at Mount Hope in Bristol, Rhode Island. He was shot and killed by an Indian named John Alderman on August 12, 1676. After his death, his wife and nine-year-old son were captured and sold as slaves in Bermuda. Philip's head was mounted on a pike at the entrance to Fort Plymouth, where it remained for more than two decades. His body was cut into quarters and hung in trees. Alderman was given Metacomet's right hand as a reward.

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1676

In Virginia, black slaves and black and white indentured servants band together to participate in Bacon's Rebellion.

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1677

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1678

The Treaty of Nijmegen ends various interconnected wars among France, the Dutch Republic, Spain, Brandenburg, Sweden, Denmark, the Prince-Bishopric of M nster, and the Holy Roman Empire.

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1679

The habeas corpus act is passed in England.

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1680

The State of Virginia forbids blacks and slaves from bearing arms, prohibits blacks from congregating in large numbers, and mandates harsh punishment for slaves who assault Christians or attempt escape.

The Pueblo Revolt drives the Spanish out of New Mexico until 1692.

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1681

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1682

What will become Pennsylvania is colonized by William Penn. Penn founds Philadelphia. Also, with other Friends, Penn purchases East Jersey.

New York makes it illegal for slaves to sell goods.

Virginia declares that all imported black servants are slaves for life.

La Salle (Ren -Robert Cavelier, Sieur de La Salle) explores the length of the Mississippi River and claims Louisiana for France.

image Peter the Great becomes joint ruler of Russia (sole tsar in 1696).

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1683

The Ottoman Empire suffered a significant defeat at the Siege of Vienna, a failed attempt to capture the city of Vienna, Austria. This marked the beginning of the empire's decline, as it was forced to cede territory and lost its status as a major European power.

The Ottoman Empire is defeated in the second Siege of Vienna.

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1684

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1685

Edict of Fontainebleau outlaws Protestantism in France. King Charles II dies.

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1686

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1687

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1688

The Pennsylvania Quakers pass the first formal antislavery resolution.

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1689

image William III ascends to the throne over England, Scotland, and Ireland.

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1690

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1691

South Carolina passes the first comprehensive slave codes.

Virginia passes the first anti-miscegenation law, forbidding marriages between whites and blacks or whites and Native Americans.

Virginia prohibits the manumission of slaves within its borders. Manumitted slaves are forced to leave the colony.

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1692

The colonies of Plymouth and Massachusetts are united.

Witchcraft mania begins to take over new England.

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1693

The College of William and Mary is founded in Williamsburg, Virginia, by a royal charter.

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1694

Rice cultivation is introduced into Carolina. Slave importation increases dramatically.

The Bank of England is established.

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1695

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1696

The Royal African Trade Company loses its monopoly and New England colonists enter the slave trade.

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1697

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1698

Calcutta is founded by the English.

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1699

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1700

image Samuel Sewall (1652-1730) publishes The Selling of Joseph — the first American protest against slavery.

Pennsylvania legalizes slavery.

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1701

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1702

New York passes An Act for Regulating Slaves. Among the prohibitions of this act are meetings of more than three slaves, trading by slaves, and testimony by slaves in court.

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1703

Delaware separates from Pennsylvania and becomes an independent colony.

Connecticut assigns the punishment of whipping to any slaves who disturb the peace or assault whites.

Massachusetts requires those masters who liberate slaves to provide a bond of 50 pounds or more in the event that the freedman becomes a public charge.

Rhode Island makes it illegal for blacks and Indians to walk at night without passes.

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1704

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1705

Massachusetts makes marriage and sexual relations between blacks and whites illegal.

New York declares that punishment by execution will be applied to certain runaway slaves.

The Virginia Slave Code codifies slave status, declaring all non-Christian servants entering the colony to be slaves. It defines all slaves as real estate, acquits masters who kill slaves during punishment, forbids slaves and free colored peoples from physically assaulting white persons, and denies slaves the right to bear arms or move abroad without written permission.

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1706

Connecticut requires that Indians, mulattos, and black servants gain permission from their masters to engage in trade.

New York declares blacks, Indians, and slaves who kill white people to be subject to the death penalty.

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1707

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1708

Africans in the colony of South Carolina outnumber Europeans, making it the first English colony with a black majority.

Blacks outnumber whites in South Carolina.

Rhode Island requires that slaves be accompanied by their masters when visiting the homes of free persons.

The Southern colonies require militia captains to enlist and train one slave for every white soldier.

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1709

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1710

New York forbids blacks, Indians, and mulattos from walking at night without lighted lanterns.

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1711

Great Britain's Queen Anne overrules a Pennsylvania colonial law prohibiting slavery.

Pennsylvania prohibits the importation of blacks and Indians.

Rhode Island prohibits the clandestine importation of black and Indian slaves.

Rio de Janeiro is captured by the French.

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1712

In Charleston, South Carolina slaves are forbidden from hiring themselves out.

New York declares it illegal for blacks, Indians, and slaves to murder other blacks, Indians, and slaves.

New York forbids freed blacks, Indians, and mulatto slaves from owning real estate and holding property.

Pennsylvania prohibits the importation of slaves.

Slave Revolt: New York Slaves in New York City kill whites during an uprising, later squelched by the militia. Nineteen rebels are executed.

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1713

England secures the exclusive right to transport slaves to the Spanish colonies in America.

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1714

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1715

Maryland declares all slaves entering the province and their descendants to be slaves for life.

Rhode Island legalizes slavery.

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1716

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1717

New York enacts a fugitive slave law.

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1718

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1719

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1720

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1721

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1722

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1723

Virginia abolishes manumissions.

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1724

Louisiana's Code Noir is enacted in New Orleans to regulate black slavery and to banish Jews from the colony

French Louisiana prohibits slaves from marrying without the permission of their owners.

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1725

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1726

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1727

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1728

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1729

The Qing Dynasty Emperor Yongzheng prohibits opium smoking in China. British refusal to comply with these anti-narcotics laws will ultimately lead to two wars (the Opium Wars) and the subjugation of China to Britain (and other western powers).

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1730

The number of male and female slaves imported to the North American British colonies balances out for the first time.

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1731

The Spanish reverse a 1730 decision and declare that slaves fleeing to Florida from Carolina will not be sold or returned.

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1732

Slaves aboard the ship of New Hampshire Captain John Major kill both captain and crew, seizing the vessel and its cargo.

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1733

Quaker Elihu Coleman's A Testimony against That Anti-Christian Practice of Maling Slaves of Men is published.

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1734

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1735

Georgia petitions Britain for the legalization of slavery.

Louis XV, King of France, declares that when an enslaved woman gives birth to the child of a free man, neither mother nor child can be sold. Further, after a certain time, mother and child will be freed.

Under an English law Georgia prohibits the importation and use of black slaves.

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1736

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1737

An indentured black servant petitions a Massachusetts court and wins his freedom after the death of his master.

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1738

Georgia's trustees permit the importation of black slaves.

Spanish Florida promises freedom and land to runaway slaves.

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1739

Slaves in Stono, South Carolina rebel, sacking and burning an armory and killing whites. Some 75 slaves in South Carolina steal weapons and flee toward freedom in Florida (then under Spanish rule). Crushed by the South Carolina militia, the revolt results in the deaths of 40 blacks and 20 whiteThe colonial militia puts an end to the rebellion before slaves are able to reach freedom in Florida.

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1740

Georgia and Carolina attempt to invade Florida in retaliation for the territory's policy toward runaways.

South Carolina passes the comprehensive Negro Act, making it illegal for slaves to move abroad, assemble in groups, raise food, earn money, and learn to read English. Owners are permitted to kill rebellious slaves if necessary.

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1741

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1742

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1743

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1744

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1745

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1746

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1747

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1748

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1749

Georgia repeals its prohibition and permits the importation of black slaves.

image Carolus Linnaeus's Philosophia Botanica rejects any notion of evolution and continues his work in classifying plants.

1750

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image Linnaeus's Species Plantarum completes his development of the use of binary nomenclature in botany. The work still provides the foundation for the modern classification of species.

image Pierre-Louis de Maupertuis's Système de la Nature provides a theoretical speculation on heredity and the origin of species by chance.

1751

Colonial South Carolina prohibits slaves from learning about or practicing medicine.

George II repeals the 1705 act, making slaves real estate in Virginia.

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1752

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1753

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1754

The French and Indian War breaks out on the North American continent between the European powers Britain and France.

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1755

image The Great Lisbon Earthquake occurs, killing more than 60,000 people. The huge earthquake (estimated at 9.0 on the modern Richter scale) strikes Lisbon, Portugal, at 9:40 am, on 1 November, during church services for All Saint's Day. Because the earthquake hits on an important church holiday and destroys almost every important church in the city, much anxiety and confusion is generated amongst the citizens of this staunch and devout Roman Catholic city and country, which had been a major patron of the Church. Theologians speculate on the religious cause and message, seeing the earthquake as a manifestation of the anger of God. Some philosophers struggle to reconcile the event with the concept that humanity lives in the best of all possible worlds — a world closely supervised by a benevolent deity.

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1756

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1757

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1758

Pennsylvania Quakers forbid their members from owning slaves or participating in the slave trade.

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1759

The British capture Québec from the French.

image Joseph Gottlieb Kölreuter'S Vorläufige nachricht von einigen das geschlecht der pflantzen betreffende versuche and beobachtungen describes his research in heredity in plants.

1760

Jupiter Hammon of Long Island, New York, publishes a book of poetry. This is believed to be the first volume written and published by an African-American

New Jersey prohibits the enlistment of slaves in the militia without their master's permission.

image King George III ascends the English throne.

Jean-Baptiste Robinet's five-volume De la nature claims that organic species form a linear scale of progress, without gaps.

image Between 1761 and 1766, Joseph Gottlieb Kölreuter (Germany) demonstrates that hybrid offspring receive traits from both parents (pollen and ovule transmit genetic information), and are intermediate in most traits. First scientific hybrid produced (tobacco). Demonstrates the identity of reciprocal crosses. Notes hybrid vigor, segregation of offspring (parental and non-parental types) from a hybrid.

1761

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image Charles Bonnet's Considerations sur les corps organisées gives his theory of "preformation" — the idea that each creature is already preformed in miniature in the egg, and that the egg contains all future generations in even smaller scale, ad infinitum.

1762

Virginia restricts voting rights to white men.

image Catherine the Great becomes Empress of all the Russias after death of her husband.

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1763

Charles Mason and Jeremiah Dixon begin surveying Mason-Dixon Line between Pennsylvania and Maryland.

image Chief Pontiac leads a Native American rebellion against British settlers in and around Detroit.

The French Indian War ends with the Treaty of Paris surrendering Canada to England.

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1764

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1765

Britain enacts Quartering Act, requiring colonists to provide temporary housing to British soldiers.

Stamp Act passed; this is the first direct British tax on colonists.

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1766

Britain repeals the Stamp Act.

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1767

Britain passes Townshend Revenue Act levying taxes on America.

The Virginia House of Burgess boycotts the British slave trade in protest of the Townsend Acts. Georgia and the Carolinas follow suit.

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1768

image Britain's Capt. James Cook begins exploring the Pacific, putting ashore in such places as New Zealand and Australia.

image Charles Bonnet's Philosophical palingenesis, or ideas on the past and future states of living beings contains his view that the females of every species contain the germs of all future generations.

1769

image Father Junipero Serra founds Mission San Diego, first mission in California.

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1770

image Crispus Attucks, an escaped slave, becomes the first colonial resident to die for American independence when he is killed by the British in the Boston massacre.

Around 1770, the European slave trade with Africa reaches its peak, transporting nearly 80,000 enslaved Africans across the Atlantic annually.

Escaped slave, Crispus Attucks, is killed by British forces in Boston, Massachusetts. He is one of the first colonists to die in the war for independence.

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1771

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1772

image On June 22, Lord Chief Mansfield rules in the James Somerset case that an enslaved person brought to England becomes free and cannot be returned to slavery. His ruling establishes the legal basis for the freeing of England's fifteen thousand slaves.

James Albert Ukawsaw Gronniosaw's writes the first autobiographical slave narrative.

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1773

Jean Baptiste Point du Sable is the first settler in the community now known as Chicago. Point du Sable described himself as "a free mulatto man." He was married to a Potawatomi woman named Catherine some time in the 1770s.

image Phillis Wheatley of Boston publishes Poems on Various Subjects, Religious and Moral. This is the first book of poetry published by an African-American woman.

Phillis Wheatley becomes the first published African-American poet when a London publishing company releases a collection of her verse.

Slaves in Massachusetts unsuccessfully petition the government for their freedom.

The first separate black church in America is founded in South Carolina.

The "Boston Tea Party" occurs as a protest against British taxation policies.

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1774

Rhode Island becomes first colony to prohibit importation of slaves.

Connecticut, Rhode Island, and Georgia prohibit the importation of slaves.

The First Continental Congress bans trade with Britain and vows to discontinue the slave trade after the 1st of December.

Virginia takes action against slave importation.

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1775

Lord Dunmore, promises freedom to male slaves who join British army.

image General Washington forbids recruiting officers enlisting blacks to fight in defense of American freedom.

image The first Spanish ship, the San Carlos, commanded by Juan Manuel de Ayala, enters San Francisco Bay.

image The Grand Union flag is adopted by the American colonies in rebellion against England.

Abolitionist Society Anthony Benezet of Philadelphia founds the world's first abolitionist society. Benjamin Franklin becomes its president in 1787.

In April, the first battles of the Revolutionary war are waged between the British and Colonial armies at Lexington and Concord, Massachusetts. Black Minutemen participate in the fighting.

In July, George Washington announces a ban on the enlistment of free blacks and slaves in the colonial army. By the end of the year, he reverses the ban, ordering the Continental Army to accept the service of free blacks.

In November, Virginia Governor John Murray, Lord Dunmore, issues a proclamation announcing that any slave fighting on the side of the British will be liberated.

The slave population in the colonies is nearly 500,000. In Virginia, the ratio of free colonists to slaves is nearly 1:1. In South Carolina it is approximately 1:2. 1775 Georgia takes action against slave importation.

Benjamin Franklin and Benjamin Rush form an anti-slavery group in Philadelphia.

The American Revolution begins with fighting at Lexington and Concord, Massachusetts.

The Continental Congress appoints George Washington head of the Continental Army.

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1776

Presidio of San Francisco forms as a Spanish fort.

Continental Congress approves enlistment of free blacks .

Delaware prohibits the importation of African slaves.

In Philadelphia, Pennsylvania, members of the Continental Congress sign the Declaration of Independence.

In Philadelphia, Pennsylvania, the Society of Friends, also known as the Quakers, forbids its members from holding slaves.

image Declaration of Independence published. The Declaration of Independence is the statement adopted by the Second Continental Congress meeting at the Pennsylvania State House (Independence Hall) in Philadelphia on July 4, 1776, which announced that the thirteen American colonies, then at war with the Kingdom of Great Britain, regarded themselves as thirteen newly independent sovereign states, and no longer under British rule. Instead they formed a new nation — the United States of America. John Adams was a leader in pushing for independence, which was passed on July 2 with no opposing vote cast. A committee of five had already drafted the formal declaration, to be ready when Congress voted on independence. The term "Declaration of Independence" is not used in the document itself. Although Americans generally regard themselves as having been independent since July 4, 1776, in fact true, legal independence was not achieved until the Treaty of Paris was signed in 1783 and ratified by the Congress of the Confederation on January 14, 1784.

image Adam Smith publishes The Wealth of Nations, which lays the foundation for free-market capitalism.

image Washington leads the Continental Army in a crossing of the Delaware River, beginning on Christmas Day. The crossing catches the British army unaware, resulting in a victory for the rebel forces.

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1777

San Jose, California, is founded on orders from Antonio María de Bucareli y Ursúa, Spanish Viceroy of New Spain, thus providing an answer to the not-yet-asked question, Do you know the way to San Jose?

image Continental Congress adopts the Stars and Stripes replacing the Grand Union flag. The new flag has thirteen stars and thirteen stripes, representing the thirteen original states: Delaware, Pennsylvania, New Jersey, Georgia, Connecticut, Massachusetts, Maryland, South Carolina, New Hampshire, Virginia, New York, North Carolina, and Rhode Island.

Vermont amends its constitution to ban slavery. Over the next 25 years, other Northern states emancipate their slaves and ban the institution: Pennsylvania, 1780; Massachusetts and New Hampshire, 1783; Connecticut and Rhode Island, 1784; New York, 1799; and New Jersey, 1804. Some of the state laws stipulate gradual emancipation.

New York enfranchises all free propertied men regardless of color or prior servitude.

Vermont is the first of the thirteen colonies to abolish slavery and enfranchise all adult males.

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1778

Rhode Island forbids the removal of slaves from the state.

Virginia prohibits the importation of slaves.

The peculiar inheritance of human color-blindness reported to The Royal Society of London by Michael Lort.

1779

image Capt. James Cook dies during a skirmish in Hawaii.

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1780

Massachusetts abolishes slavery and grants African-American men the right to vote.

A freedom clause in the Massachusetts constitution is interpreted as an abolishment of slavery. Massachusetts enfranchises all men regardless of race.

Delaware makes it illegal to enslave imported Africans.

Pennsylvania begins gradual emancipation.

Great Hurricane of 1780 — the deadliest Atlantic hurricane on record — kills 20,000 to 30,000 in Caribbean.

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1781

Los Angeles, California, is founded by 54 settlers, including 26 of African ancestry.

image Immanuel Kant publishes Critique of Pure Reason, a fundamental work of modern philosophy.

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1782

Britain signs agreement recognizing U.S. independence.

Congress approves Great Seal of U.S. and the eagle as its symbol.

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1783

American Revolution Ends Britain and the infant United States sign the Peace of Paris treaty.

Earthquakes ravage Calabria in Italy, killing 30,000.

(no entry for this year)

1784

John Jay becomes first U.S. Secretary of State.

Russian trappers established a colony on Kodiak Island, Alaska.

Congress narrowly defeats Thomas Jefferson's proposal to ban slavery in new territories after 1800.

Treaty of Paris ratified, officially ending the American Revolutionary War

Congress of the Confederation ratifies the Treaty of Paris on January 14, 1784, formally ending the Revolutionary War.

John Wesley charters Methodist Church.

(no entry for this year)

1785

New York frees all slaves who served in the Revolutionary Army.

Napoleon Bonaparte (16) graduates from the military academy in Paris (42nd in a class of 51).

(no entry for this year)

1786

image Frederick the Great, King of Prussia, dies.

(no entry for this year)

1787

image Federalist Papers published, calls for ratification of Constitution. The Federalist (later known as The Federalist Papers) is a collection of 85 articles and essays written (under the pseudonym Publius) by Alexander Hamilton, James Madison, and John Jay promoting the ratification of the United States Constitution. Seventy-seven were published serially in the Independent Journal and the New York Packet between October 1787 and August 1788. A compilation of these and eight others, called The Federalist: A Collection of Essays, Written in Favour of the New Constitution, as Agreed upon by the Federal Convention, September 17, 1787, was published in two volumes in 1788 by J. and A. McLean. The collection's original title was The Federalist; the title The Federalist Papers did not emerge until the 20th century. This book should be carefully read by anyone with an interest in American democracy.

Constitutional convention opens at Philadelphia, George Washington presiding.

The Northwest Ordinance bans slavery in the Northwest Territory (what becomes the states of Ohio, Indiana, Illinois, Michigan, and Wisconsin). The ordinance together with state emancipation laws create a free North.

Austrian emperor Jozef II bans children under 8 from labor.

(no entry for this year)

1788

Maryland votes (December 23) to cede a ten-square-mile area for District of Columbia.

New York City becomes first capital of US.

The Massachusetts General Court (legislature), following an incident in which free blacks were kidnapped and transported to the island of Martinique, declares the slave trade illegal and provides monetary damages to victims of kidnappings.

Captain Arthur Phillip forms English colony at Sydney, Botany Bay, New South Wales, Australia.

image Kant publishes Critique of Practical Reason.

image Johann Wolfgang Goethe's Versuch, die Metamorphose der Pflanzen zu erklären (Attempt to explain the metamorphosis of plants) claims incorrectly that all plant structures are modified leaves, but clearly espouses evolution.

1789

US Congress passes Federal Judiciary Act, creating a six-person Supreme Court.

image George Washington becomes the first president of the United States.

image Fletcher Christian leads Mutiny on HMS Bounty and Captain William Bligh. Mutineers from the Bounty settle on Pitcairn Island.

image Former slave Olaudah Equiano publishes his memoirs, and he travels in Britain lecturing against slavery.

The fall of the Bastille marks the beginning of the French Revolution.

(no entry for this year)

1790

First U.S. census is conducted, showing a population of 3,939,214.

Society of Friends petitions Congress for abolition of slavery.

The first ten amendments to the US Constitution — The Bill of Rights — are ratified.

Washington, D.C., founded as the capitol of the United States.

(no entry for this year)

1791

Vermont admitted as 14th state (first addition to the original thirteen colonies).

(no entry for this year)

1792

image The Coinage Act of 1792 (also known as the Mint Act; officially: An act establishing a mint, and regulating the Coins of the United States), passed by the United States Congress on April 2, 1792, created the United States dollar as the country's standard unit of money, established the United States Mint, and regulated the coinage of the United States. This act established the silver dollar as the unit of money in the United States, declared it to be lawful tender, and created a decimal system for U.S. currency. The Act specified the issuing of three gold coins comprising a $10 gold coin called an "eagle", a $5 coin called a "half eagle", and a $2.5 coin called a "quarter eagle". The Act also authorized construction of a mint building in Philadelphia, the nation's capital at the time. This was the first federal building erected under the United States Constitution. Adjusted for inflation, the ten-dollar coin would be worth $231.00 in today's money. As collector's items, these gold coins have sold for more than $100,000 each.

U.S. postal service created; postage 6–12 cents, depending on distance. (In today's dollars, that would be somewhere between $1.40 and $3.00.)

Captain George Vancouver claims Puget Sound for Britain.

France declares war on Austria, starting French Revolutionary Wars.

The French Republic is proclaimed.

Twenty-four merchants form New York Stock Exchange at 70 Wall Street.

(no entry for this year)

1793

To enforce Article IV, Section 2, the U.S. Congress enacts the Fugitive Slave Law. It allows slaveowners to cross state lines to recapture their slaves. They must then prove ownership in a court of law. In reaction, some Northern states pass personal liberty laws, granting the alleged fugitive slaves the rights to habeas corpus, jury trials, and testimony on their own behalf. These Northern state legislatures also pass anti-kidnapping laws to punish slave-catchers who kidnap free blacks, instead of fugitive slaves.

image King Louis XVI of France is executed.

image Erasmus Darwin (Charles' grandfather) publishes Zoonomia, or the Laws of Organic Life.

James Hutton publishes An Investigation of the Principles of Knowledge. Buried in the 2,138-page philosophical tome is a chapter about variety in nature in which Hutton anticipates Charles Darwin's theory of natural selection.

image John Dalton's Extraordinary facts relating to the vision of colors gives an early account of red-green color blindness, which he refers to as Daltonism, since he is afflicted with the condition.

1794

Slavery abolished in the French colonies.

image James Hutton's Theory of the Earth published, interpreting certain geological strata as former sea beds. Hutton proposes geological theory of gradualism.

1795

image The US flag is modified to have fifteen stars and fifteen stripes, reflecting the addition of two new states: Vermont and Kentucky. This is the only US flag to have other than thirteen stripes.

(no entry for this year)

1796

George Washington declines a third term as President, gives his Farewell Address.

image Publication of Thomas Malthus' Essay on the Principle of Population, a work that Darwin asserted helped him frame the principle of evolution by natural selection.

1798

Napoleon invades Egypt and defeats the Egyptians at the Battle of the Pyramids.

image The first mammoth fossil fully documented by modern science is discovered near the delta of the Lena River in 1799 by Ossip Schumachov, a Siberian hunter. Schumachov allows it to thaw (a process taking several years) until he can retrieve the tusks for sale to the ivory trade in Yakutsk. He then abandons the specimen, allowing it to decay before its recovery. In 1806, Russian botanist Mikhail Adams rescues what remained of the specimen and brought it to the Zoological Museum of the Zoological Institute of the Russian Academy of Sciences in St. Petersburg. The specimen, which became known as the Adams Mammoth, is stuffed and mounted, and continues to be on display at the Zoological Institute.

Charles White publishes An Account of the Regular Gradation in Man, and in Different Animals and Vegetables, a treatise on the great chain of being, showing people of color at the bottom of the human chain.

1799

image The Rosetta Stone is discovered in Egypt. The stone is a fragment of an Egyptian stele with the same inscription in three texts: ancient Egyptian hieroglyphs, Egyptian demotic script, and Greek. This side-by-side translation allows historians to translate ancient Egyptian hieroglyphs for the first time.

image Napoleon Bonaparte becomes First Consul and seizes power in France.

(no entry for this year)

1800

(no entry for this year)

image Jean-Baptiste Lamarck's Système de Animaux sans Vertèbres (System for Animals without Vertebrae) includes a classification system for invertebrates and a preliminary view of his ideas of evolution.

1801

image Thomas Jefferson becomes the third president of the United States.

Ireland and Great Britain, England and Scotland, form United Kingdom.

In Natural Theology, William Paley uses the analogy of a watch requiring a watchmaker to argue that the universe implies an intelligent designer.

1802

The Ohio Constitution outlaws slavery. It also prohibits free blacks from voting.

(no entry for this year)

1803

U.S. President Thomas Jefferson appoints Meriwether Lewis and William Clark to explore the uncharted West. Among the marvels Lewis and Clark are expected to find are erupting volcanoes, mountains of salt, unicorns, living mastodons and seven-foot-tall beavers. They will find none of these, but will find fossils.

image US buys large tract of land from France — The Louisiana Purchase.

(no entry for this year)

1804

image image Meriwether Lewis and William Clark begin their exploration of the Louisiana territory.

(no entry for this year)

1805

image Britain's Lord Nelson defeats the Franco-Spanish fleet at the Battle of Trafalgar. Lord Nelson is killed, but his victory ends Napoleons power at sea and makes a French invasion of Britain impossible.

(no entry for this year)

1806

(no entry for this year)

(no entry for this year)

1807

The Slave Trade Act 1807 or the Abolition of the Slave Trade Act 1807, was an Act of the Parliament of the United Kingdom passed on 25 March 1807, with the title of "An Act for the Abolition of the Slave Trade". The original act is in the Parliamentary Archives. The act abolished the slave trade in the British Empire, in particular the Atlantic slave trade, and also encouraged British action to press other European states to abolish their slave trades, but it did not abolish slavery itself.

(no entry for this year)

1808

United States Bans Slave Trade Importing African slaves is outlawed, but smuggling continues.

The US prohibits the importation of new slaves from Africa (but the holding of existing slaves and their descendents remains legal).

image 12 Feb 1809

Charles Darwin is born

image Jean Baptiste de Lamarck's theory of evolution presented with the publication of his Philosophie Zoologique, which emphasized the fundamental unity of life and the capacity of species to vary.

1809

(no entry for this year)

1810

(no entry for this year)

(no entry for this year)

1811

"Luddites" destroy industrial machines in North England, in protest over too rapid modernization.

(no entry for this year)

1812

Between 1812 and 1815, the United States and Great Britain fight the War of 1812.

Napoleon invades Russia; he captures Moscow, but unable to spend the winter there when the city catches fire, he marches his army back to France, experiencing tremendous losses along the way.

US declares war on Britain — War of 1812 begins.

image Swiss-French botanist Augustin Pyramus de Candolle introduces the word TAXONOMY in his lifelong project of a 21-volume plant encyclopedia. Seven volumes are published during his lifetime, the remainder after his death.

1813

(no entry for this year)

(no entry for this year)

1814

image The British army burns down the White House in Washington DC.

The defeat of the Creeks by Andrew Jackson begins the forced departure of Indian peoples from the South.

(no entry for this year)

1815

image Three thousand troops of the United States Army, led by General Andrew Jackson, defeat the British at the Battle of New Orleans. Six hundred of the US troops are African-American.

image image An Allied army, led by Britain's Duke of Wellington, defeats Napoleon at the Battle of Waterloo.

(no entry for this year)

1816

Shaka becomes ruler of the Zulu Kingdom; his disciplined and mobile army conquers many peoples of southeastern Africa.

image Georges Cuvier's Le règne animal distribué d'après son organisation (The animal kingdom, distributed according to its organization) gives an account of the whole animal kingdom, dividing it into four distinct groups.

1817

(no entry for this year)

1818

image The US flag is modified to have twenty stars, reflecting the addition of five new states: Indiana, Louisiana, Mississippi, Ohio, and Tennessee. The number of stripes is returned to thirteen (both to symbolize the original thirteen states and to avoid having the number of stripes get so large that the flag would seem pink). From this point on, the US flag will have the same overall design, with changes in the number of stars used to denote the addition of new states.

1819

image The US flag is modified to have twenty-one stars, reflecting the addition of one new state: Illinois.

The Canadian government refuses to cooperate with the American government in the apprehension of fugitive slaves living in Canada. Consequently Canada becomes the destination for 40,000 fugitive slaves from United States between 1819 in 1861.

image The SS Savannah was an American hybrid sailing ship/side-wheel steamer built in 1818. She becomes the first steamship to cross the Atlantic Ocean, a feat accomplished during May–June, 1819. The Savannah was converted back into a sailing ship after returning from Europe. She was wrecked of Long Island in 1821.

The United States purchases Florida from Spain.

image Christian Friedrich Nasse formulated Nasse's law: hemophilia occurs only in males and is passed on by unaffected females.

1820

image The US flag is modified to have twenty-three stars, reflecting the addition of two new states: Alabama and Maine.

Debate over slavery in the US heats up; The Missouri Compromise admits Maine into the Union as a free state, with Missouri to enter the next year as a slave state. Slavery is banned north of the 36 30' line of latitude in the Louisiana Territory.

Missouri Compromise Missouri is admitted to the Union as a slave state, Maine as a free state. Slavery is forbidden in any subsequent territories north of latitude .

The first Christian missionaries arrived in the Hawaiian Islands.

(no entry for this year)

1821

(no entry for this year)

Etienne Geoffroy publishes Anatomical Philosophy discussing similarities between skeletal structures — such as bat wings, paws and hands — that support the evolutionary claims of Lamarck. He also argues that arthropods and vertebrates have similar but inverse body plans, an assertion that will ultimately be widely accepted.

image Between 1822-1824, Thomas Andrew Knight, John Goss, and Alexander Seton all independently perform crosses with the pea and observe dominance in the immediate progeny, and segregation of various hereditary characters in the next generation. However, they do not study later generations or determine the numerical ratios in which the characters are transmitted.

1822

image The US flag is modified to have twenty-four stars, reflecting the addition of one new state: Missouri.

Slave Revolt: South Carolina Freed slave Denmark Vesey attempts a rebellion in Charleston. Thirty-five participants in the ill-fated uprising are hanged.

image Thomas Andrew Knight confirms reports of dominance, recessivity, and segregation in peas, but does not detect regularities.

1823

Slavery is abolished in Chile.

(no entry for this year)

1824

Mexico outlaws slavery. This decision creates the incentive for Anglo Texans to fight for independence in 1835-1836.

Mexico becomes a republic, three years after declaring independence from Spain.

(no entry for this year)

1826

(no entry for this year)

image Karl Ernst von Baer first demonstrated the mammalian ovum; he regarded the sperm cells as "Entozoa," i.e., parasites, and named them spermatozoa.

1827

(no entry for this year)

A year after discovering the mammalian egg cell, Karl Ernst von Baer publishes Entwickelungsgeschichte der Thiere tracing the developmental history of animals.

image Publication of Karl Ernst von Baer's The Embryology of Animals which strongly opposed preformationism.

1828

(no entry for this year)

(no entry for this year)

1829

image Charles Lyell's multi-volume Principles of Geology appear (between 1830 amd 1833), advancing the theory of uniformitarianism, i.e., the view that geological formations are explainable in terms of forces and conditions observable at present.

1830

image On April 6, the Church of Jesus Christ of Latter-Day Saints is founded by Joseph Smith Jr. (1805-1844), in Fayette, New York. In Palmyra, New York, The Book of Mormon is published for the first time; Smith has translated it, he says, from golden tablets he found buried near Palmyra.

The first wagon trains to cross the Rocky Mountains arrived in California.

The U.S. Congress passes the Indian Removal Act.

The world's population tops 1,000,000,000 (it had been roughly 750 million only 50 years earlier).

image Charles Darwin joins the crew of the HMS Beagle as the ship's naturalist. The Beagle plans a two-year voyage to map the coast of South America. This turns out to be a five-year trip.

Patrick Matthew publishes On Naval Timber and Arboriculture with an appendix describing what Charles Darwin will later name natural selection. After becoming aware of Matthew's hypothesis, Darwin will acknowledge it in a reprint of On the Origin of Species.

image Robert Brown published his observations reporting the discovery and widespread occurrence of nuclei in cells.

1831

Nat Turner leads a slave rebellion in Southampton, Virginia, killing at least 57 whites. Hundreds of black slaves are killed in retaliation.

Alabama makes it illegal for enslaved or free blacks to preach.

image In Boston, William Lloyd Garrison founds the abolitionist newspaper, The Liberator, signaling a dramatic shift in the antislavery movement. In the previous decades, it had centered in the South and favored a combination of compensated emancipation and colonization of freed slaves back to Africa. In the 1830s, the abolitionist movement becomes the dominant voice among antislavery advocates. Abolitionists demand the immediate end to slavery, which they consider to be a moral evil, without compensation to slaveowners.

Nat Turner, a literate slave who believes he is chosen to be the Moses of his people, instigates a slave revolt in Virginia. He and his followers kill 57 whites, but the revolt is unsuccessful and up to 200 slaves are killed. After an intense debate, the Virginia legislature narrowly rejects a bill to emancipate Virginia's slaves. The widespread fear of slave revolts, compounded by the rise of abolitionism, leads legislatures across the South to increase the harshness of their slave codes. Also, expressions of anti-slavery sentiment are suppressed throughout the South through state and private censorship.

North Carolina enacts a statute that bans teaching enslaved people to read and write.

Slave Revolt: Virginia Slave preacher Nat Turner leads a two-day uprising against whites, killing about 60. Militiamen crush the revolt then spend two months searching for Turner, who is eventually caught and hanged. Enraged Southerners impose harsher restrictions on their slaves.

(no entry for this year)

1832

Oberlin College is founded in Ohio. It admits African-Americans. By 1860, one third of its students are black.

image Electric telegraph invented by Samuel Morse.

image The first volume of the five-volume Recherches sur les poissons fossiles (Researches on Fossil Fishes) by Jean-Louis-Rodolphe Agassiz is published.

1833

The American Anti-Slavery Society is established in Philadelphia.

The British Parliament abolishes slavery in the entire British Empire.

(no entry for this year)

1834

South Carolina bans the teaching of blacks, and slave or free, in its borders.

Federal troops are ordered to put down a riot by workers along the Chesapeake and Ohio Canal. It is the first time federal troops have been used to settle a labor battle in the United States.

image While serving as scientific officer on the HMS Beagle, Charles Darwin visits the Galapagos Islands. He observes that the many varieties of finches on the islands seem to have developed from a common ancestor found on the mainland of South America.

1835

Texas declares its independence from Mexico. In its constitution as an independent nation, Texas recognizes slavery and makes it difficult for free blacks to remain there.

Southern states expel abolitionists and forbid the mailing of antislavery propaganda.

image The first volume of La Dèmocracie en Amèrique (Democracy in America), by Alexis de Tocqueville (1805-1859), is published in France. Tocqueville, a historian and politician and member of the French aristocracy, writes about the American people and their institutions, based on his 9 months of travels through the United States and eastern Canada in 1831-1832.

(no entry for this year)

1836

image The US flag is modified to have twenty-five stars, reflecting the addition of one new state: Arkansas.

image Davy Crockett killed, as Texans are defeated by the Mexican army at the Alamo.

image In Paris, the Arc de Triomphe is completed. The arch was ordered built by Napoleon in 1806.

image Texas gains independence from Mexico after winning the battle of San Jacinto.

Charles Darwin formulates the theory of natural selection to explain evolution. Fearful of the reaction his theory will cause, he delays publishing.

1837

image The US flag is modified to have twenty-six stars, reflecting the addition of one new state: Michigan.

image Martin Van Buren becomes eighth president of the United States.

image William IV, King of Great Britain, dies.

image image M. J. Schleiden and T. Schwann develop the cell theory. Schleiden notes nucleoli within nuclei.

1838

image Coronation of Victoria as queen of Great Britain.

(no entry for this year)

1839

image La Amistad was a 19th-century two-masted schooner, owned by a Spaniard living in Cuba. It became renowned in July 1839 for a slave revolt by Mende captives, who had been enslaved in Sierra Leone, and were being transported from Havana, Cuba to their purchasers' plantations. The African captives took control of the ship, killing some of the crew and ordering the survivors to sail the ship to Africa. The Spanish survivors secretly maneuvered the ship north, and La Amistad was captured off the coast of Long Island by the brig USS Washington. The Mende and La Amistad were interned in Connecticut while federal court proceedings were undertaken for their disposition. The owners of the ship and Spanish government claimed the slaves as property; but the US had banned the African trade and argued that the Mende were legally free. Because of issues of ownership and jurisdiction, the case gained international attention. Former president John Quincy Adams argued on behalf of the slaves when the appeal was brought before the U.S. Supreme Court, which eventually determined the Africans to be free men. The case became a symbol in the United States in the movement to abolish slavery.

Sultan Abdulmecid I implemented the Tanzimat reforms in an attempt to modernize the Ottoman Empire and strengthen it against European powers. The reforms included changes to the legal system, education, and the military, and were influenced by western ideas.

image image In response to the British opium trade, Lin Zexu wrote a letter to Queen Victoria, urging her to end the opium trade: We find that your country is sixty or seventy thousand li from China. Yet there are barbarian ships that strive to come here for trade for the purpose of making a great profit. The wealth of China is used to profit the barbarians. That is to say, the great profit made by barbarians is all taken from the rightful share of China. By what right do they then in return use the poisonous drug to injure the Chinese people? Even though the barbarians may not necessarily intend to do us harm, yet in coveting profit to an extreme, they have no regard for injuring others. Let us ask, where is your conscience? The letter to the Queen never reached her. Belatedly, it was delivered and published in The Times of London.

image Lin Zexu was a Chinese scholar-official of the Qing dynasty best known for his role in the First Opium War of 1839 42. In March 1839, Lin arrived in Guangdong Province to take measures that would eliminate the opium trade. He was a formidable bureaucrat known for his competence and high moral standards, with an imperial commission from the Daoguang Emperor to halt the illegal importation of opium by the British. Upon arrival, he made changes within a matter of months. He arrested more than 1,700 Chinese opium dealers and confiscated over 70,000 opium pipes. He initially attempted to get foreign companies to forfeit their opium stores in exchange for tea, but this ultimately failed. Lin resorted to using force in the western merchants' enclave. A month and a half later, the merchants gave up nearly 1.2 million kg (2.6 million pounds) of opium. Beginning 3 June 1839, 500 workers laboured for 23 days to destroy it, mixing the opium with lime and salt and throwing it into the sea outside of Humen Town. Lin composed an elegy apologising to the gods of the sea for polluting their realm.

The First Opium War between Britain and China occurs between 1839 and 1842, triggered when Chinese officials attempt to prevent the sale of narcotics (opium) to the Chinese people by the British East India trading Company. The British respond by bringing in gunboats and shelling Chinese coastal cities.

image The process of vulcanization, developed by Charles Goodyear, makes possible the commercial use of rubber.

image Charles Darwin's Zoology of the Voyage of the Beagle appears.

Martin Barry expressed the belief that the spermatozoon enters the egg.

1840

(no entry for this year)

(no entry for this year)

1841

image William Henry Harrison becomes ninth president of the United States; dies one month after inauguration.

The U.S.S. Creole, a ship carrying slaves from Virginia to Louisiana, is seized by the slaves on board and taken to Nassau, where they are free.

image John Tyler becomes tenth president of the United States.

image The first centralized government bureau of statistics is founded in Belgium by the mathematician Lambert Adolphe Jacques Quetelet (1781-1840).

image Charles Darwin's book The Structure and Distribution of Coral Reefs being the first part of the geology of the voyage of the Beagle, is published. During the year Darwin composes an abstract of his theory of species evolution.

image Carl Wilhelm von Nägeli (1817-1891) publishes Zur Entwicklungsgeschichte des Pollens. His paper describes cell division in plants with remarkable accuracy, and discusses seed formation in flowering plants.

1842

image Frederick Douglass leads a successful campaign against Rhode Island's proposed Dorr Constitution, which would have continued the prohibition on black male voting rights.

In Prigg v. Pennsylvania, the U.S. Supreme Court upholds the Fugitive Slave Law of 1793, stating that slaveowners have a right to retrievetheir "property." In so doing, the court rules that Pennsylvania's anti-kidnapping law is unconstitutional. At the same time, the Supreme Court declares that enforcement of the Fugitive Slave Lawis a federal responsibility in which states are not compelled to participate. Between 1842 and 1850, nine Northern states pass new personal liberty laws which forbid state officials from cooperating in the return of alleged fugitive slaves and bar the use of state facilities for that purpose.

Slavery is abolished in Uruguay.

The Virginia Legislature votes against abolishing slavery.

In Commonwealth v. Hunt, a case involving the Boston Journeyman Bootmakers Society, the Chief Justice of the Massachusetts Supreme Court ruled that trade unions are legal. The ruling revises the common law that treated such unions as criminal conspiracies.

The Massachusetts State Legislature enacts a child labor law that limits the working hours of children under 12 years-old to 10 hours per day.

P. T. Barnum lures crowds of thousands to see his "Feejee Mermaid."

(no entry for this year)

1843

image Sequoyah, Cherokee Indian leader, creates Cherokee syllabary and develops the first written form of a native North American language.

image Congress grants S. F. B. Morse $30,000 to build the first telegraph line (Washington to Baltimore).

image Charles Darwin first outlines his thoughts on natural selection in an unpublished essay.

image Robert Chambers, a Scottish journalist, publishes (anonymously) his Vestiges of the Natural History of Creation, an early book outlining an evolutionary view of the natural world.

image The second part of the Geology of the Beagle, Charles Darwin's Geological Observations on Volcanic Islands Visited During the Voyage of H.M.S. Beagle, is published. Darwin's book claims to supply evidence for the geological theories of Charles Lyell (1797-1875), from areas that Lyell himself had never seen.

image That all the cells in an organism are generated from successive divisions of the egg cell is described by Rudolf Albert von Kölliker (1817-1905). Kölliker shows that the egg is itself a cell.

1844

(no entry for this year)

(no entry for this year)

1845

image The US flag is modified to have twenty-seven stars, reflecting the addition of one new state: Florida.

image Frederick Douglass publishes his autobiography, The Life and Times of Frederick Douglass.

image James K. Polk becomes eleventh president of the United States.

Texas is annexed by the United States.

The Irish potato famine begins, one of the century's worst natural disasters. One million citizens starve to death, and one million others emigrate, mostly to the United States

(no entry for this year)

1846

image The US flag is modified to have twenty-eight stars, reflecting the addition of one new state: Texas.

Mexican-American War Defeated, Mexico yields an enormous amount of territory to the United States. Americans then wrestle with a controversial topic: Is slavery permitted in the new lands?

The first professional baseball game is played, in Hoboken, New Jersey.

The Mexican War (1846-48) between the United States and Mexico results in the United States taking possession of California and much of the Southwest, which had been Mexican territory.

The Oregon Treaty delineates border between the United States and Canada.

Jakob Mathias Schleiden and Theodor Schwann announce that cells are the basic units of all living structures.

1847

image The US flag is modified to have twenty-nine stars, reflecting the addition of one new state: Iowa.

image The North Star, an abolitionist newspaper, begins publication in Rochester, New York. The paper is founded by escaped slave Frederick Douglass (1817-1895), with money he earned as a result of his autobiography.

Liberia is formed as a home for released American slaves.

Missouri bans the education of free blacks.

The Istanbul slave market is abolished.

The Factory Act is passed in Britain. It forbids women and children between the ages of 13 and 18 to work more than 10 hours per day.

image The first United States postage stamps are issued

image On the archetype and homologies of the vertebrate skeleton, by Richard Owen (1804-1892), is published. In the book Owen argues that the skull, and other parts of the body, are formed by the modification of the vertebra of different animals.

Richard Owen describes "homologies" — similarities of design in bird wings, fish fins and human hands.

1848

image The US flag is modified to have thirty stars, reflecting the addition of one new state: Wisconsin.

Slavery is abolished in old French and Danish colonies.

image Karl Marx publishes The Communist Manifesto, which asserts that revolution by the working classes will ultimately destroy capitalism.

Revolution breaks out across much of Europe; the Second Republic is proclaimed in France.

image Botanist Carl Friedrich von Gärtner (1772-1850) publishes Versuche und Beobachtungen über die Bastarderzeugung im Pflanzenreiche. The book describes thousands of experiments, many involving the production of hybrids, on more than 500 species of plants. Mendel will study this book in detail when he attends the University of Vienna in the early 1850s, and will cite the book in the opening of his paper of 1865.

1849

image Charles Lewis Reason becomes the first African-American college instructor when he is hired at predominantly white Free Mission College (later New York Central College) to teach Greek, Latin, French, and mathematics.

image Harriet Tubman escapes from slavery and goes on to lead more than 300 slaves to freedom on the underground railroad.

image Zachary Taylor becomes twelfth president of the United States.

The California gold rush begins as more than 100,000 people swarm to California to make their fortunes after gold is found there in 1848.

Showmen Moses Kimball and P. T. Barnum purchase the contents of the Peale Museum (established in 1784).

(no entry for this year)

1850

The Compromise of 1850 is introduced into Congress by Henry Clay as an omnibus bill designed to settle disputes arising from the conclusion of the Mexican War. It passes after Stephen Douglas divides the bill into several parts: California enters the Union as a free state; the slave trade (but not slavery) is abolished in Washington D.C.; the fugitive slave law is strengthened; and the Utah and New Mexico Territories are opened to slavery on the basis of popular sovereignty (allowing territorial voters to decide the issue without federa linterference).

image Millard Fillmore becomes the thirteenth president of the United States, when Zachary Taylor dies in office.

(no entry for this year)

1851

image The US flag is modified to have thirty-one stars, reflecting the addition of one new state: California.

(no entry for this year)

1852

image The French Republic falls; Louis Napoleon (Napoleon III) is crowned Emperor.

The U.S. state of Massachusetts adopts a compulsory school-attendance law, the first effective example of such a law in the nation.

(no entry for this year)

1853

image Commodore Matthew Perry sails into Japan's Edo Bay with his black ships (four modern, steam-powered warships), urging Japan to open trade policies with the United States.

image Franklin Pierce becomes fourteenth president of the United States.

(no entry for this year)

1854

Kansas-Nebraska Act: In an attempt to spur population growth in the western territories in advance of a transcontinental railroad, Stephen Douglas introduces a bill to establish the territories of Kansas and Nebraska. In order to gain Southern support, the bill stipulates that slavery in the territories will be decided by popular sovereignty. Thus the Kansas-Nebraska Act repeals the Missouri Compromise ban on slavery north of 36 30' in the lands of the Louisiana Purchase.

Ostend Manifesto: The U.S. ministers to Britain, France, and Spain meet in Ostend, Belgium. They draft a policy recommendation to President Pierce, urging him to attempt again to purchase Cuba from Spain and, if Spain refuses, to take the island by force. When the secret proposal, called the Ostend Manifesto, is leaked to the press, it creates an uproar since Cuba would likely become another slave state.

image On May 24, Virginia fugitive slave Anthony Burns is captured in Boston and returned to slavery under the provisions of the Fugitive Slave Act. Fifty thousand Boston residents watch his transport through the streets of the city in shackles. A Boston church raises $1500 to purchase his freedom and Burns returns to the city in 1855, a free man.

On May 30, the Kansas-Nebraska act is passed by Congress. The act repeals the Missouri Compromise and permits the admission of Kansas and Nebraska territories to the Union after their white male voters decide the fate of slavery in those territories.

Slavery is abolished in Peru and Venezuela.

The Republican Party is formed in the summer in opposition to the extension of slavery into the western territories.

image Alfred Russel Wallace publishes "On the Law which has Regulated the Introduction of New Species," anticipating Darwin's theory of evolution by natural selection.

image Rudolf Virchow states the principle that new cells come into being only by division of previously existing cells: Omnis cellula e cellula.

1855

The Massachusetts Legislature outlaws racially segregated schools.

image The remains of the first known example of what come to be known as the "Neanderthals" is found in a cave near Düsseldorf, in the Neander Valley. The discovery was made by limestone quarry miners and consists of a skullcap, two femora, the three right arm bones, two of the left arm bones, ilium, and fragments of a scapula and ribs. The fossils were given to Johann Carl Fuhlrott, a local teacher and amateur naturalist. The first description of the remains was made by anatomist Hermann Schaaffhausen and the find was announced jointly in 1857.In 1997, the specimen was the first to yield Neanderthal mitochondrial DNA fragments. The description of this discovery represents the beginning of paleoanthropology as a scientific discipline.

Louis Agassiz publishes Essay on Classification advocating a theory of multiple creations and contradicting both evolution and Noah's ark.

image Gregor Mendel, a monk at the Augustinian monastery of St. Thomas in Brünn, Austria (now Brno, Czechoslovakia), begins breeding experiments with the garden pea, Pisum sativum.

1856

image The Caning of Charles Sumner: Senator Charles Sumner delivers a stinging speech in the U.S. Senate, "The Crime against Kansas," in which he attacks slavery, the South, and singles out his Senate colleague, Andrew Butler of South Carolina, for criticism. In retaliation, Butler's nephew, Congressman Preston Brooks of South Carolina, attacks Sumner with a cane while the Massachusetts senator is seated at his desk on the floor of the Senate. The injuries he sustains cause Sumner to be absent from the Senate for four years. The episode revealed the polarization in America, as Sumner became a martyr in the North and Brooks a hero in the South. Northerners were outraged. Southerners sent Brooks hundreds of new canes in endorsement of his assault. One was inscribed "Hit him again." Brooks claimed that he had not intended to kill Sumner, or else he would have used a different weapon. In a speech to the House defending his actions, Brooks stated that he "meant no disrespect to the Senate of the United States" or the House by his attack on Sumner. He was tried in a District of Columbia court, convicted for assault, and fined $300 ($8,000 in today's dollars), but received no prison sentence.

In South Africa, Boers establish the South African Republic (Transvaal), with Pretoria as its capital. Marthinus Wessels Pretorius, 37, is named the first president.

The Second Opium War (1856-1860) between Britain and China leads to further erosion of Chinese sovereignty.

(no entry for this year)

1857

image Farmer Hinton Rowan Helper publishes The Impending Crisis of the South, and How to Meet It, in which he argues that slavery in economically unwise, and particularly devastating to small farmers who do not own slaves. He writes that slavery is "the root of all the shame, poverty, ignorance, tyranny and imbecility" in the South. He also argues that slavery foolishly ties up economic resources in human beings when it might be spent on labor-saving improvements.

The African slave trade is prohibited in the Ottoman Empire

image The Dred Scott Decision makes the Missouri Compromise unconstitutional and increases tension between North and South over slavery in the United States. Writing for the majority, Chief Justice Roger B. Taney asserted that blacks were "beings of an inferior order, and altogether unfit to associate with the white race, either in social or political relations, and so far inferior that they had no rights which the white man was bound to respect." This embarrassing decision represents a low point in the history of the United States Supreme Court.

image James Buchanan becomes fifteenth president of the United States.

image Giuseppe Garibaldi, who returned to Italy in 1854 after several years working at Staten Island, New York, founds the Italian National Association. The organization is designed to promote the unification of Italy.

Rudolf Virchow finalizes the cell theory originally announced by Schleiden and Schwann 11 years earlier by declaring that cells are the basic units of all living things, and all cells are formed by the division of existing cells.

image Alfred Russel Wallace sends to Darwin a manuscript — "On the Tendency of Varieties to Depart Indefinitely from the Original Type" — that shows clearly that Wallace has independently formulated a model of evolution by natural selection.

image image Darwin's and Wallace's ideas are jointly presented to the Linnaean Society of London.

1858

image The US flag is modified to have thirty-two stars, reflecting the addition of one new state: Minnesota.

image Abraham Lincoln, running for the United States Senate, declares "A house divided against itself cannot stand." He loses the race to Stephen Douglas, but his performance in there now-legendary debates leads to his nomination as the Republican candidate for president in 1860.

In Ireland, the group Sein Féin is founded.

image Charles Darwin publishes On the Origin of Species.

1859

image The US flag is modified to have thirty-three stars, reflecting the addition of one new state: Oregon.

Harriet Wilson of Milford, New Hampshire, publishes Our Nig; or Sketches from the Life of a Free Black, the first novel by an African-American woman.

image On October 16, John Brown leads 20 men, including five African-Americans, in an unsuccessful attempt to seize the Federal Armory at Harper's ferry, Virginia, with the goal of inspiring a slave insurrection. He was captured by US troops under the command of Colonel Robert E. Lee, tried, and hanged on December 2.

image Louis Agassiz attacks Darwin's the origin of species, rejecting the idea of evolution of the species and arguing that each species was created separately.

image Thomas Henry Huxley (sometimes known as Darwin's bulldog) clashes with Bishop "Soapy Sam" Wilberforce about evolution at the annual meeting of The British Association for the Advancement of Science, in what has come to be known as the Huxley-Wilberforce debate.

Bishop Wilberforce is supposed to have asked Huxley sarcastically whether "it was through his grandfather or his grandmother that he claimed descent from a monkey." Huxley responded, "If then the question is put to me whether I would rather have a miserable ape for a grandfather or a man highly endowed by nature and possessed of great means of influence and yet employs these faculties and that influence for the mere purpose of introducing ridicule into a grave scientific discussion, I unhesitatingly affirm my preference for the ape." Or words to that effect.

1860

On December 20, South Carolina secedes from the union, setting in motion the forces leading to the US Civil war.

Southern Secession South Carolina secedes in December. More states follow the next year.

The Pony Express begins cross-country mail delivery.

image image Between 1861 and 1862, Max Johann Sigismund Schultze (Germany) and Heinrich Anton de Bary (Germany) establish the essential unity of protoplasm in all living cells.

1861

image Abraham Lincoln becomes sixteenth president of the United States.

Fort Sumter shelled, American Civil War begins.

The First Battle of Bull Run, also known as the First Battle of Manassas (the name used by Confederate forces and still often used in the Southern United States), is fought on July 21, 1861, near Manassas, Virginia. It is the first major land battle of the American Civil War. Neither Confederate nor Union troops were ready for battle. Union troops advanced on Confederate troops, almost breaking through, but at the last moment, Confederate reinforcements arrived on the battlefield and carried the day. Union troops were routed. Union civilian spectators, who had come to watch the expected Confederate defeat as entertainment, were forced to run for their lives.

image The US flag is modified to have thirty-four stars, reflecting the addition of one new state: Kansas.

United States Civil War Four years of brutal conflict claim 623,000 lives.

Congress passes the First Confiscation Act, which prevents Confederate slave owners from re-enslaving runaways.

(no entry for this year)

1862

On April 16, Congress abolishes slavery in the District of Columbia.

image Otto von Bismarck is appointed Prime Minister of Prussia.

image The Battle of Fort Donelson (11-16 Feb) is an early Union victory in the American Civil War, which opened the Cumberland River as an avenue for the invasion of the South. The success elevated Brig. Gen. Ulysses S. Grant from an obscure and largely unproven leader to the rank of major general.

The Battle of Shiloh (6-7 Apr). Although the Confederates swept the field on the first day, Union troops under U. S. Grant retook the field on the second day. Combined Union and Confederate casualties (23,746 killed, wounded, or missing) represented more than the total American battle-related casualties of the American Revolutionary War, the War of 1812, and the Mexican-American War combined.

Alfred Russel Wallace describes the "Wallace line," the dividing line between Indo-Malayan and Austro-Malayan fauna, in Proceedings of the Royal Geographical Society of London.

image image Dominique Alexandre Godron and Charles Victor Naudin (France) independently report experiments in plant hybridization. Naudin confirmed Sageret's work, in general discussed work of the early hybridizers, and reported dominance and segregation in Datura (jimsonweed) hybrids. He did not deal with single characters and reported no statistical observations on the second generation. His theoretical explanation of his facts was a forerunner of Mendel's ideas, but inferred rather than deduced.

1863

image The US flag is modified to have thirty-five stars, reflecting the addition of one new state: West Virginia. This new state was created when Union sympathizers in the western portion of Virginia seceded from Virginia (then in secession from the US) and rejoined the Union.

Abraham Lincoln's Emancipation Proclamation takes effect on January 1, legally freeing slaves in areas of the South still in rebellion against the United States.

image The Battle of Gettysburg (1-3 Jul) was the battle with the largest number of casualties in the American Civil War. Union Maj. Gen. George Gordon Meade's Army of the Potomac defeated attacks by Confederate Gen. Robert E. Lee's Army of Northern Virginia, ending Lee's invasion of the North.

image image The Siege of Vicksburg was the final major military action in the Vicksburg Campaign of the American Civil War. Union Maj. Gen. Ulysses S. Grant crossed the Mississippi River and drove the Confederate army of Lt. Gen. John C. Pemberton into the fortress city of Vicksburg, Mississippi, and placed the city under siege. After more than forty days, with no re-enforcement and supplies nearly gone, the garrison surrendered on July 4. This surrender, combined with Lee's defeat at Gettysburg the previous day, represents the turning point of the war. From then on, military victory for the Confederacy was impossible.

(no entry for this year)

1864

image After the Confederate defeat at Chattanooga, President Lincoln promoted Grant to a special regular army rank, Lieutenant General, authorized by Congress on March 2, 1864. This rank had previously been awarded two other times, a full rank to George Washington and a Brevet rank to Winfield Scott. Lincoln then places Grant in charges of all Union forces.

image image image Sherman captures Atlanta, marches to Savannah. Through a series of bloody battles, Grant forces Lee back to Petersburg, Virginia, and then lays siege to the city. Lincoln is reelected, destroying the South's hope for a political settlement to the war.

Franz Schweigger-Seidel and A. von la Valette St. George (Germany) independently prove that a spermatozoon is a single cell and contains nucleus and cytoplasm

image Gregor Mendel presents his work on inheritance in peas to the Brünn Natural History Society. The results are published the following year.

1865

On February 1, Abraham Lincoln signs the 13th Amendment to the United States Constitution outlawing slavery throughout the United States.

The Thirteenth Amendment to the United States Constitution officially abolished slavery and involuntary servitude, except as punishment for a crime. It was passed by the Senate on April 8, 1864, passed by the House on January 21, 1865, and adopted on December 6, 1865.

Lee surrenders, US Civil war ends, Lincoln assassinated.

image Andrew Johnson becomes seventeenth president of the United States.

image The US flag is modified to have thirty-six stars, reflecting the addition of one new state: Nevada.

image The Ku Klux Klan is formed on December 24 in Polanski, Tennessee, by six Confederate veterans. Nathan Bedford Forrest, a former Confederate cavalry general and slave trader, serves as the Klan's first grand wizard or leader-in-chief.

German zoologist Ernst Haeckel publishes General Morphology of Organisms, the first detailed genealogical tree relating all known organisms, incorporating the principles of Darwinian evolution.

image Ernst Heinrich Haeckel (Häckel) hypothesizes that the nucleus of a cell transmits its hereditary information.

image Mendel publishes his work on heredity, Versuche über Pflanzen Hybriden.

1866

On June 13, Congress approves the Fourteenth Amendment to the Constitution, guaranteeing due process and equal protection under the law to all citizens. The amendment also grants citizenship to African-Americans.

H. S. Bidwell (United States) reports controlled pollination in maize.

1867

image The US flag is modified to have thirty-seven stars, reflecting the addition of one new state: Nebraska.

The Alaska Purchase resulted in the transfer of Alaska to the United States from the Russian Empire for a total price of $ 7,000,000. The purchase, made at the initiative of United States Secretary of State William H. Seward, gained 586,412 square miles of new United States territory.

image Charles Darwin publishes The Variation of Animals and Plants under Domestication, in which he offers his own theory of heredity, which he called the "Provisional Hypothesis of Pangenesis."

Ernst Haeckel publishes Natürliche Schöpfungsgeschichte, subdividing humanity into 12 separate species. He also asserts that evolution consists of 22 phases, the 21st being the "missing link" between apes and humans.

Thomas Henry Huxley publishes "On the Animals which are Most Nearly Intermediate between Birds and Reptiles," arguing that birds are descendants of dinosaurs. This suggestion will not be taken very seriously for another century.

1868

The Meiji Restoration in Japan (led by samurai from the western clans of Satsuma, Choshu, Tosa, and Hizen) overthrows the feudal shogunate system and initiates Japan's participation in the modern world.

The Impeachment of Andrew Johnson, 17th President of the United States, was one of the most dramatic events in the political life of the United States during Reconstruction, and the first impeachment in history of a sitting United States president.

image Francis Galton publishes Hereditary Genius. In it he describes a scientific study of human pedigrees from which he concludes that intelligence has a genetic basis.

1869

On February 26, Congress sends the Fifteenth Amendment to the Constitution to the states for approval. The amendment guarantees African-American males the right to vote.

Transcontinental Rail Service Begun in the United States On May 10th, at Promontory Point, Utah, a golden rail spike was struck, completing the first transcontinental railroad line.

image Ulysses S. Grant becomes eighteenth president of the United States.

image Japan colonizes Hokkaido as part of its new nation state.

image The Suez Canal opened to traffic on 17 November. The canal linked the Mediterranean and the Red Sea. It was 103 miles long and it brought Oriental ports 5,000 miles closer to Europe. Work had begun on the canal in 1859, financed primarily by French investors. The canal increased the strategic importance of Egypt to European powers.

(no entry for this year)

1870

image Standard Oil Formed On January 10th, 1870, John D Rockefeller and four partners incorporate the Standard Oil Company. The company gains control of nearly 95% of the oil refining industry in the United States.

The First Vatican Council of the Roman Catholic Church proclaims the dogma of the infallibility of the Pope.

The Franco-Prussian war (1870-71) leads to the formation of the German Empire.

image Publication of Charles Darwin's Descent of Man, in which the role of sexual selection in evolution is described for the first time.

Lord Kelvin suggests that "the germs of life might have been brought to the Earth by some meteorite," an idea that will enjoy support a century later.

image Johann Friedrich Miescher isolates a substance which he calls NUCLEIN from the nuclei of white blood cells. The substance was soluble in alkalis but not in acids and came to be known as nucleic acid.

image Lambert Adolphe Jacques Quetelet showed the importance of statistical analysis for biologists and laid the foundation of biometry.

1871

image On October 8th, a fire broke out in the west side of Chicago. The Great Chicago Fire lasted two days, killing 300 people, and destroying most of Chicago. Property damages were estimated at 200 million dollars.

On October 8th, a fire broke out in the village of Peshtigo, Wisconsin. The Peshtigo Fire caused more deaths than any other fire in the history of the United States. By the time it was over, 1,875 square miles (1.2 million acres) of forest had been consumed, an area approximately twice the size of the state of Rhode Island. Some sources list as much as 1.5 million acres burned. Twelve communities were destroyed. An accurate death toll has never been determined since local population records were destroyed in the fire. Between 1,200 and 2,500 people are thought to have lost their lives.

The occurrence of this fire, and several other smaller fires, on the same day as the Great Chicago fire has lead some to speculate that all of the fires may have had a common cause: multiple impacts from fragments of a disintegrating comet.

image image Henry Morton Stanley finds David Livingstone in Africa, greeting the Scotsman with the famous words, "Dr. Livingstone, I presume."

The Second Reich proclaimed With the German victory in France complete, the German Reichstag(parliament) proclaimed the creation of the Second Reich. The Reichstag approved with minor modification the constitution of the Northern German Federation. William I became King of Germany with Otto Bismarck the first chancellor.

image Ferdinand Julius Cohn coined the term BACTERIUM and founded the study of bacteriology.

1872

(no entry for this year)

image Anton Schneider observed and described the behavior of nuclear filaments (chromosomes) during cell division in his study of the platyhelminth Mesostoma. His account was the first accurate description of the process of mitosis in animal cells.

1873

Slavery is abolished in Puerto Rico.

Spain decrees the end of slavery in Cuba, still a Spanish colony.

(no entry for this year)

1874

(no entry for this year)

image Eduard Strasburger accurately described the processes of mitotic cell division in plants.

image Francis Galton demonstrates the usefulness of twin studies for elucidating the relative influence of nature (heredity) and nurture (environment) upon behavioral traits.

image Oscar Hertwig concludes from a study on sea urchins that fertilization in both animals and plants consists of the physical union of the two nuclei contributed by the male and female parents.

1875

(no entry for this year)

(no entry for this year)

1876

image Custer Killed at Little Bighorn On June 25th, in Dakota territory, at the Little Big Horn, General George Armstrong Custer (who graduated from West Point in 1861, last in his class) and all 256 troops were killed. The defeat of Custer in the Battle of the Little Big Horn was the last Indian victory.

image Alexander Graham Bell patents the telephone.

image Hermann Fol reports watching the spermatozoan of a starfish penetrate the egg. He was able to see the transfer of the intact nucleus of the sperm into the egg, where it became the male pronucleus.

1877

The Compromise of 1877 ends Reconstruction and gives the Presidency to Rutherford B. Hayes. Although Democratic presidential candidate Samuel Tilden won the popular vote, Southern Democratic leaders agreed to support Rutherford Hayes' efforts to obtain the disputed electoral votes of Florida, Louisiana, and South Carolina in exchange for the withdrawal of the last federal troops from the South and the end of federal efforts to protect the civil rights of African Americans.

image Rutherford B. Hayes becomes nineteenth president of the United States.

image The US flag is modified to have thirty-eight stars, reflecting the addition of one new state: Colorado.

Frederick Douglass becomes US Marshal for the District of Columbia.

image Wilhelm Friedrich Kühne proposed the term ENZYME (meaning "in yeast") and distinguished enzymes from the micro-organisms that produce them.

1878

image image Thomas Edison and Joseph Wilson Swan produce first successful incandescent electric light.

image From 1879 through 1882, Walther Flemming describes and names CHROMATIN, MITOSIS, and the SPIREME. He makes the first accurate counts of chromosome numbers and accurately drew the "longitudinal splitting" of chromosomes.

1879

image F. W. Woolworth opens his first "five and dime store".

image image image Throughout the decade of 1880-1890, Walther Flemming, Eduard Strasburger, Edouard van Beneden, and others elucidate the essential facts of cell division and stressed the importance of the qualitative and quantitative equality of chromosome distribution to daughter cells.

1880

(no entry for this year)

(no entry for this year)

1881

image James A Garfield becomes twentieth president of the United States.

Six months after taking office, Garfield becomes the second US President to be assassinated, when he was shot by Charles J. Guiteau — a disgruntled and impoverished would-be office holder. When he purchased the pistol used in the assassination, he chose to buy one with an ivory handle because he thought it would look good as a museum exhibit after the assassination.

In January, the Tennessee State Legislature votes to segregate railroad passenger cars.

image On the Fourth of July, Booker T. Washington opens Tuskegee Institute in central Alabama.

image Chester A. Arthur becomes twenty-first president of the United States.

image Clara Barton founds the American Red Cross.

Walther Flemming publishes accurate depictions of cell division (mitosis) in Zellsubstanz, Kern und Zelltheilung.

image Eduard Strasburger coins the terms CYTOPLASM and NUCLEOPLASM.

image W. Flemming discovers lampbrush chromosomes and coins the term MITOSIS.

1882

Britain Invades Egypt The British invaded Egypt in response to anti foreign riots. The British defeated the army of Arabi Pasha at Al Tell. On September 15th they captured Cairo. Arabi pasha the nationalist leader was deported to Ceylon.

image August Weismann points out the distinction in animals between the somatic cell line and the germ cells, stressing that only changes in germ cells are transmitted to further generations.

image Edouard van Beneden announced the principles of genetic continuity of chromosomes and reported the occurrence of chromosome reduction at germ cell formation. The sperm and egg are haploid and fertilization restores the diploid chromosome number.

image Wilhelm Roux offers a possible explanation for the function of mitosis.

image William Keith Brooks, a professor at The Johns Hopkins University, publishes The Law of Heredity: A Study of the Cause of Variation and the Origin of Living Organisms. Although this speculative work did not significantly advance the understanding of heredity, brooks' thinking is important because during his career he provided instruction to and supervised the early research of Thomas H. Morgan, Edmund Beecher Wilson, and William Bateson — ultimately some of the most important contributors to the new science of genetics.

1883

On October 16, the United States Supreme Court declares invalid the Civil Rights Act of 1875, stating that the federal government cannot bar corporations or individuals from discriminating on the basis of race.

image On May 25, the New York boroughs of Manhattan and Brooklyn were linked with the opening of the Brooklyn Bridge. The bridge was the first steel suspension bridge erected in the United States. It was built at a cost of $16 million and 26 lives. When it opened, the Brooklyn Bridge was the longest suspension bridge in the world.

image image image image During 1884-88, identification of the cell nucleus as the basis for inheritance was independently reported by Oscar Hertwig, Eduard Strasburger, Albrecht von Kölliker, and August Weismann.

image Gregor Mendel dies on January 6th, without ever knowing that his work on peas would lead to the transformation of biological research.

image image image Walther Flemming, Eduard Strasburger and Edouard van Beneden demonstrate that chromosome doubling occurs by a process of longitudinal splitting. Strasburger describes and names the PROPHASE, METAPHASE, and ANAPHASEstages of chromosomal division.

1884

(no entry for this year)

image August Weismann formulates the germ-plasm theory which held that the germ plasm was separate from the somatoplasm and was continuous from generation to generation.

image Carl Rabl theorized the individuality of chromosomes in all stages of the cell cycle.

image Walther Flemming observed sister chromatids passing to opposite poles of the cell during mitosis.

1885

image Francis Galton devised a new useful statistical tool, the correlation table.

image Hugo de Vries (Holland) discovers aberrant evening primrose plants at Hilversum, Holland. Experiments with these extending over 15 years formed the basis for his mutation theory of evolution.

1886

Slavery is abolished in Cuba.

Daimler produces his first car.

image August Weismann elaborated an all-encompassing theory of chromosome behavior during cell division and fertilization and predicted the occurrence of a reduction division (meiosis) in all sexual organisms.

image Edouard van Beneden demonstrated chromosome reduction in gamete maturation, thereby confirming August Weismann's predictions.

image Wilhelm Roux put forth the suggestion that the linearly arranged qualities of the chromosomes were equally transmitted to both daughter cells at meiosis.

1887

African-American players are banned from major league baseball.

Slavery is abolished in Brazil

Interstate Commerce Act Passed On February 4, President Cleveland signed into law the first bill regulating the railroads. The act, which called for just and equal rates, also limited pooling (secret pacts between railroads). This measure received broad support in the Congress.

The United States acquires Pearl Harbor, Hawaii, as a coaling station and future naval base.

German anatomist W. von Waldeyer names chromosomes.

image Heinrich Wilhelm Gottfried von Waldeyer names the CHROMOSOME.

image Theodor Boveri verifies August Weismann's predictions of chromosome reduction by direct observation in Ascaris.

1888

image George Eastman Patents Camera George Eastman patents the hand held camera.

Slavery is abolished in Brazil, bringing to an end of the legal sanction of slavery in the Americas.

image Francis Galton publishes Natural Inheritance. In it he describes the quantitative measurement of metric traits in populations. He thus founds biometry and the statistical study of variation. Ultimately, he formulates the Law of Ancestral Inheritance, a statistical description of the relative contributions to heredity made by one's ancestors.

1889

Florida becomes the first state to use the poll tax to disenfranchise black voters.

image Frederick Douglass is appointed minister to Haiti.

image Benjamin Harrison becomes twenty-third president of the United States.

Oklahoma Land Rush The last major unsettled territory in the United States (which had been exclusively Indian) is opened for settlement. Over 200,000 settlers gather at the borders of the territory awaiting the opportunity to seize land. On the first day the territory was opened, 12,000 settlers arrived in Guthrie, Oklahoma.

image The numerical equality of paternal and maternal chromosomes at fertilization was established by Theodor Boveri and Jean-Louis-Léon Guignard.

1890

image About 60 common starlings are released into New York's Central Park by Eugene Schieffelin, as part of an effort to introduce every bird species mentioned in the works of William Shakespeare into North America. The original 60 birds have since swelled in number to 150 million, occupying an area extending from southern Canada and Alaska to Central America.

image The US flag is modified to have forty-three stars, reflecting the addition of five new states: Idaho, Montana, North Dakota, South Dakota, and Washington.

The United States Army massacres 200 Indians at Wounded Knee in South Dakota, ending the Indian wars of resistance.

(no entry for this year)

1891

image The US flag is modified to have forty-four stars, reflecting the addition of one new state: Wyoming.

The first basketball game is played, in Springfield, Massachusetts.

image Publication of August Weismann's book Das Keimplasma (The Germ Plasm) emphasized meiosis as an exact mechanism of chromosome distribution.

1892

A record 230 people are lynched in the United States this year; 161 are black and 69 white.

image Hans Driesch expounded the view that all nuclei of an organism were equipotential but varied in their activity in accordance with the differentiation of tissues.

image Karl Pearson published the first in a long series of contributions to the mathematical theory of evolution. Methods for analyzing statistical frequency distributions were developed in detail.

image William Bateson's Materials for the Study of Variation emphasized the importance of discontinuous variations, foreshadowing the rediscovery of Mendel's work.

1894

(no entry for this year)

(no entry for this year)

1895

The Lumiere Brothers introduce moving pictures.

The Sino-Japanese War ends and Japan gains dominance over Korea and Taiwan.

image E. B. Wilson publishes The Cell in Development and Heredity. This influential treatise (ultimately reprinted in several editions) distills the information compiled concerning cytology in the half-century since Schleiden and Schwann put forth the cell theory.

1896

image The US flag is modified to have forty-five stars, reflecting the addition of one new state: Utah.

In Plessy vs. Ferguson, the United States Supreme Court declares legalized segregation in the United States to be constitutional.

image The will of Alfred Nobel establishes annual prizes for peace, science, and literature.

(no entry for this year)

1897

image William McKinley becomes twenty-fifth president of the United States. McKinley was the last veteran of the Civil war to serve as President. He enlisted as a private in the 23rd Ohio Infantry, and by the end of the war he had been promoted several times, finally leaving the service with the rank of Captain.

image Zionist activity begins in the Middle East, under the World Zionist Congress called by Theodore Herzl.

(no entry for this year)

1898

The United States Supreme Court, in Williams vs. Mississippi, rules that poll taxes and literacy tests do not violate the Constitution.

United States invades Cuba and defeats Spain in the Spanish-American War.

image image L. Cuénot (France) working with animals, and Strasburger (Germany) working with plants, advance theory that sex is controlled within the germ cell, not by environment.

Richard Altmann renames "nuclein" as NUCLEIC ACID.

The First International Congress of Genetics held in London.

image William Bateson writes a paper on hybridisation and cross-breeding as a method of scientific investigation that anticipates Mendel's rediscovery.

1899

The Boer war breaks out between Afrikaners and the British in southern Africa.

image H. de Vries adopts the term MUTATION to describe sudden, spontaneous, drastic alterations in the hereditary material of Oenothera.

T. H. Montgomery studies spermatogenesis in various species of Hemiptera. He concludes that maternal chromosomes only pair with paternal chromosomes during meiosis.

1901

image Theodore Roosevelt becomes twenty-sixth president of the United States.

image Queen Victoria dies and is succeeded by her son, Edward VII.

image Archibald Garrod, a British physician, reports that alkaptonuria (a human disease) seems to be inherited as a Mendelian recessive.

image C. E. McClung argues that particular chromosomes determine the sex of the individual carrying them, not just in insects, but perhaps in other species (including man).

image Walter Sutton concludes that (a) chromosomes have individuality, (b) that they occur in pairs, with one member of each pair contributed by each parent, and (c) that the paired chromosomes separate from each other during meiosis.

image T. Boveri studies sea urchin embryos and finds that in order to develop normally, the organism must have a full set of chromosomes, and from this he concludes that the individual chromosomes must carry different essential hereditary determinants.

image William Bateson coins terms that will become essential to describing findings in the new science of heredity: GENETICS, F1, F2, ALLELOMORPH (later shortened to ALLELE), HOMOZYGOTE, HETEROZYGOTE, and EPISTASIS.

1902

(no entry for this year)

image The concepts of PHENOTYPE, GENOTYPE, and SELECTION were introduced and clearly defined by Wilhelm Ludwig Johannsen.

1903

image W. E. B. Du Bois' The Souls of Black Folk is published on April 27. Du Bois rejects the gradualism of Booker T. Washington and calls for agitation on behalf of African-American rights.

image Orville and Wilbur Wright succeed with the first controlled flight in a heavier-than-air machine.

(no entry for this year)

1904

image Ota Benga, a young Mbuti man from the Belgian Congo, is exhibited at the St. Louis world's fair and with the primate collection at the Bronx zoo.

The Russo-Japanese war begins with a surprise attack by the Imperial Japanese Navy against the Russian far East Fleet, while it was at anchor at Port Arthur.

K. S. Merezhkovsky suggests that chloroplasts originated as a cyanobacterium swallowed by a protozoan, i.e., algal and plant cells result from two independent organisms that became symbionts. The idea will be largely forgotten until it is suggested again in the 1960s.

image Lucien Claude Cuénot performs crosses between mice carrying a gene that gives them yellow fur. Since they always produce yellow furred and agouti offspring in a 2:1 ratio, he concludes they are heterozygous. (In 1910, W. E. Castle and C. C. Little will show that yellow homozygotes die in utero. This dominant allele is thus the first gene shown to behave as a homozygous lethal.)

1905

image An obscure Swiss patent clerk, Albert Einstein, formulates the special theory of relativity and ushers in the atomic age.

The National Forest Service is established in the United States by Gifford Pinchot.

image image William Bateson and Reginald Crundall Punnett report the discovery of two new genetic principles: LINKAGE and GENE INTERACTION.

1906

image An All-India Muslim League is founded by Sultan Mahommed Shah, Aga Khan III.

image Mount Vesuvius erupts, devastating the town of Ottaiano, Italy

The Great San Francisco Earthquake kills seven hundred people and causes more than $400 million in property losses.

The world's largest battleship — the Satsuma — is launched in Japan.

(no entry for this year)

1907

image Alain Locke of Philadelphia, a Harvard graduate, becomes the first African-American Rhodes scholar to study at Oxford University in England.

Robert Baden-Powell founds the Boy Scout movement, in Britain.

image Godfrey Harold Hardy, a Cambridge mathematician, writes a letter to the editor of Science, suggesting that Mendelian mechanisms acting alone have no effect on allele frequencies. The letter begins, I am reluctant to intrude in a discussion concerning matters of which I have no expert knowledge, and I should have expected the very simple point which I wish to make to have been familiar to biologists. However,... This short (less than one page) letter constitutes Hardy's entire lifetime contribution to the field of biology, yet still forms the mathematical basis for population genetics.

1908

image The US flag is modified to have forty-six stars, reflecting the addition of one new state: Oklahoma.

The Young Turk revolution restores the Constitution and parliamentary government in the Ottoman Empire.

image T. H. Morgan, later to become the first recipient of the Nobel Prize for work in genetics, writes a paper expressing doubts about the profusion of Mendelian explanations for inherited properties.

image A. E. Garrod publishes Inborn Errors of Metabolism, the earliest discussion of the biochemical genetics of man (or any other species).

image George H. Shull advocates the use of self-fertilized lines in production of commercial seed corn. The hybrid corn program that resulted, created an abundance of foodstuffs worth billions of dollars.

H. Nilsson Ehle puts forward the multiple-factor hypothesis to explain the quantitative inheritance of seed-coat color in wheat.

image W. Johannsen's studies of the inheritance of seed size in self-fertilized lines of beans leads him to realize the necessity of distinguishing between the appearance of an organism and its genetic constitution. He invents the terms PHENOTYOPE and GENOTYPE to serve this purpose, and he also coins the word GENE.

1909

The National Association for the Advancement of Colored People (NAACP) is formed on February 12 in New York City.

image William Howard Taft becomes twenty-seventh president of the United States.

Tel Aviv, the first Jewish town in modern Palestine, is founded.

image United States explorer Commander Robert E. Peary, accompanied by Matthew Henson, is the first person to reach North Pole.

1910

image On July 4, boxer Jack Johnson defeats Jim Jeffries in Reno, Nevada, to become the first African-American world heavyweight champion.

1911

image A fire inside the Triangle Shirtwaist Company factory in New York City's garment district kills 146 workers, mostly immigrant Jewish and Italian women in their teens and early 20s. Most women could not escape the burning building because the doors to the stairwells and exits were locked to keep the workers from stealing linen from the factory. It is the deadliest workplace incident in the city's history until 9/11.

Winston Churchill is appointed First Lord of the Admiralty.

(no entry for this year)

1912

image The US flag is modified to have forty-eight stars, reflecting the addition of two new states: Arizona and New Mexico.

image On April 10, the RMS Titanic — the largest, most advanced, and most luxurious passenger ship in the world — set off on her maiden voyage from Southampton, England to New York City. Four days later, this unsinkable marvel of modern engineering rammed an iceberg and sank in the North Atlantic, resulting in the deaths of 1,517 people.

image image The Republic of China is a nationally proclaimed with Sun Yat-sen as president. He appoints Chiang Kai-shek as his military advisor.

image A. H. Sturtevant, an undergraduate working with Morgan at Columbia, provides the experimental basis for the linkage concept in Drosophila and produces the first GENETIC MAP.

1913

image Woodrow Wilson becomes twenty-eighth president of the United States.

On April 11, President Woodrow Wilson initiates the racial segregation of workplaces, restaurants, and lunchrooms and all federal offices across the nation.

The federal income tax is introduced in the United States with the 16th amendment.

1914

The Ottoman Empire entered World War I on the side of the Central Powers, fighting against the Allied Powers. The war proved costly for the empire, leading to economic hardship, military defeats, and ultimately, its dissolution.

World War I begins after Archduke Francis Ferdinand, heir to the Austrian throne, and his wife are assassinated in Sarajevo, Bosnia, on June 28 by a Serbian nationalist.

image Calvin Bridges identifies strains of mutant fruit flies with extra pairs of wings. Decades later, these strains will help biologists understand Hox genes that control the head-to-toe anatomy of widely varying animals.

image Frederick Twort discovers a virus capable of infecting and destroying bacteria.

image image image image Thomas Hunt Morgan, Alfred Henry Sturtevant, Calvin Blackman Bridges, and Hermann Joseph Muller publish The Mechanism of Mendelian Heredity. This monograph provides the first systematic description of the actual mechanisms that control inheritance as evidenced in the Mendelian model. Here, for the first time, the gene is made real.

1915

(no entry for this year)

(no entry for this year)

1916

image image The Sykes–Picot Agreement (a secret agreement between the governments of the UK and France defining their respective spheres of influence and control in the Middle East after the expected downfall of the Ottoman Empire during World War I) is drawn up and signed by Sir Mark Sykes and Fran ois Georges-Picot.

image British polymath D'Arcy Wentworth Thompson publishes On Growth and Form arguing that the forms Darwinian natural selection can produce through evolution are constrained by physical and mathematical laws, and that organic structures often emulate inorganic natural structures. His analysis led the way for the scientific explanation of morphogenesis, the process by which patterns and body structures are formed in plants and animals. Thompson's description of the mathematical beauty of nature and the mathematical basis of the forms of animals stimulated thinkers as diverse as Julian Huxley, Conrad Hal Waddington, Alan Turing, Claude Lévi-Strauss, Eduardo Paolozzi, Le Corbusier, and Mies van der Rohe.

image C. B. Bridges discovers the first chromosome deficiency in Drosophila.

image Felix Hubert D'Herelle, independently of Frederick Twort, discovers a virus capable of infecting and destroying bacteria, which he calls a BACTERIOPHAGE.

1917

image Lucy Diggs Slowe wins the championship in the first national tennis tournament sponsored by the American Tennis Association. With her victory she becomes the first African-American woman to win a major sports title.

image The Balfour Declaration (dated 2 November 1917) — a formal statement of policy by the British government, written by Arthur Balfour, stating that "His Majesty's government view with favour the establishment in Palestine of a national home for the Jewish people, and will use their best endeavours to facilitate the achievement of this object" — is issued. The anniversary of the declaration, 2 November, is widely commemorated in Israel and among Jews in the Jewish diaspora as Balfour Day. This day is also observed as a day of mourning in Arab countries still today.

The October Revolution occurs in Russia, followed by the Russian Civil War.

image The United States enters World War I; Gen. Pershing goes to Paris to lead American forces.

(no entry for this year)

1918

image A worldwide influenza epidemic strikes. By 1920, 50 to 100 millions are dead, including Mark Sykes, the author of the British half of the Sykes-Picot Treaty.

image Thomas Hunt Morgan and coworkers publish The Physical Basis of Heredity, a book-length summary of the rapidly growing findings in genetics.

image C. B. Bridges discovers chromosomal duplications in Drosophila.

image T. H. Morgan calls attention to the equality in Drosophila melanogaster between the number of linkage groups and the haploid number of chromosomes.

1919

By the beginning of 1919, the Ku Klux Klan (revived in 1915 at Stone Mountain, Georgia) operates in 27 states. Eighty-three African Americans are lynched during the year, among them a number of returning soldiers still in uniform.

(no entry for this year)

1920

Women gain the right to vote in the United States.

The Russian Civil War ends in victory for the Bolsheviks.

Lillian V. Morgan discovers attached-X chromosomes in Drosophila.

1922

image The Dyer Anti-Lynching Bill (first introduced by St. Louis congressman Leonidas Dyer in 1918), making lynching a federal offense, passes the US House of Representatives but fails in the US Senate.

The Ottoman Empire officially ended with the signing of the Treaty of Lausanne, which recognized the sovereignty of the Republic of Turkey. Mustafa Kemal Ataturk, the founder of the Turkish Republic, implemented sweeping reforms to modernize the country and break with the Ottoman past.

A. E. Boycott and C. Diver describe "delayed" Mendelian inheritance controlling the direction of the coiling of the shell in the snail Limnea peregra. A. H. Sturtevant suggests that the direction of coiling of the Limnea shell is determined by the character of the ooplasm, which is in turn controlled by the mother's genotype.

image C. B. Bridges discovers chromosomal translocations in Drosophila.

1923

Harding dies in office.

image Calvin Coolidge becomes thirtieth president of the United States.

Adolf Hitler's attempted coup d'état (the Beer Hall Putsch) in Munich fails. Hitler is imprisoned for eight months

(no entry for this year)

1924

image Gandhi undertakes his 21-day fast to protest feuds between Hindus and Muslims in India.

Tennessee schoolteacher John Thomas Scopes is tried for teaching evolution in the famous "Scopes Monkey Trial." Two-time presidential candidate William Jennings Bryan leads the prosecution. Labor lawyer Clarence Darrow leads the defense and goads Bryan into declaring that humans are not mammals. The conviction will be overturned on a technicality, and the anti- evolution law will remain on the books for decades.

image A. H. Sturtevant analyzes the Bar-eye phenomenon in Drosophila and discovers position effect.

1925

image On September 9, Ossian Sweet, a Detroit physician, is arrested for murder after he and his family kill a member of a white mob while defending their home. The Sweet family is represented by Clarence Darrow and they are acquitted of the charge.

Hitler reorganizes the Nazi party and publishes volume one of Mein Kampf.

Ibn Saud of Najd conquers Hijaz and forms Saudi Arabia.

A. H. Sturtevant finds the first inversion in Drosophila.

1926

Hirohito takes over the Japanese throne upon the death of his father, Yoshihito.

image Mussolini takes total control in Italy, banning all opposition.

image Bernard O. Dodge initiates genetic studies on Neurospora.

image H. J. Muller reports the artificial induction of mutations in Drosophila by x-rays.

image J. B. S. Haldane suggests that the genes known to control certain coat colors in various rodents and carnivores may be evolutionarily homologous.

1927

(no entry for this year)

image Frederick Griffith discovers type-transformation of pneumococci. This lays the foundation for the work of Avery, MacLeod, and McCarthy (1944).

image L. J. Stadler reports the artificial induction of mutations in maize, and demonstrates that the dose-frequency curve is linear.

1928

(no entry for this year)

(no entry for this year)

1929

image Herbert Hoover becomes thirty-first president of the United States.

Black Tuesday in New York signals the beginning of a worldwide economic crisis and the beginning of the Great Depression, when the US stock exchange collapses, losing $26 billion in value.

image R. A. Fisher publishes Genetical Theory of Natural Selection, a formal analysis of the mathematics of selection.

1930

(no entry for this year)

C. Stern, and independently H. B. Creighton and B. McClintock, provide the cytological proof of crossing over.

1931

(no entry for this year)

(no entry for this year)

1932

(no entry for this year)

Robert Broom publishes The Coming of Man: Was it Accident or Design? arguing that evolution is really driven by spiritual agencies, some with conflicting priorities, and that mankind is the ultimate aim of all evolution.

image T. H. Morgan receives a Nobel Prize in Medicine for his development of the theory of the gene. He is the first geneticist to receive this award.

image Barbara McClintock demonstrates in maize that a single exchange within the inversion loop of a paracentric inversion heterozygote generates an acentric and a dicentric chromatid.

T. S. Painter initiates cytogenetic studies on the salivary gland chromosomes of Drosophila.

1933

image Franklin D. Roosevelt becomes thirty-second president of the United States.

Adolf Hitler is appointed German Chancellor; later the same year he is granted dictatorial powers. Events are in motion that will lead to World War II — the greatest military struggle of all time.

(no entry for this year)

1934

image In Herndon vs Georgia, the United States Supreme Court sets aside the death sentence of black communist Angelo Herndon, who was convicted under a pre-Civil War slave insurrection statute for passing out leaflets in Atlanta.

image C. B. Bridges publishes the salivary gland chromosome maps for Drosophila melanogaster.

G. W. Beadle and B. Ephrussi and A. Kuhn and A. Butenandt work out the biochemical genetics of eye-pigment synthesis in Drosophila and Ephestia, respectively.

image J. B. S. Haldane is the first to calculate the spontaneous mutation frequency of a human gene.

1935

(no entry for this year)

A. H. Sturtevant and T. Dobzhansky publish the first account of the use of inversions in constructing a chromosomal phylogenetic tree.

1936

image Track star Jesse Owens wins four gold medals at the Berlin Olympics between August 3 and August 9.

German troops occupy the Rhineland in defiance of the treaties of Locarno and Versailles.

T. Dobzhansky publishes Genetics and the Origin of Species — a milestone in evolutionary genetics.

1937

(no entry for this year)

(no entry for this year)

1938

(no entry for this year)

E. L. Ellis and M. Delbrück perform studies on coliphage growth that mark the beginning of modem phage work. They devise the "one-step growth" experiment, which demonstrates that after the phage adsorbs onto the bacterium, it replicates within the bacterium during the "latent period," and finally the progeny are released in a "burst."

1939

image August 23, the Molotov–Ribbentrop Pact, officially the Treaty of Non-Aggression between Germany and the Union of Soviet Socialist Republics, and also known as the Hitler–Stalin Pact and the Nazi–Soviet Pact, was a non-aggression pact between Nazi Germany and the Soviet Union, with a secret protocol establishing Soviet and German spheres of influence across Northern Europe. The pact was signed in Moscow by Soviet Foreign Minister Vyacheslav Molotov and German Foreign Minister Joachim von Ribbentrop. One week after signing the pact, on 1 September 1939, Germany invaded Poland.

image September 1, Germany invades Poland; Britain and France declare war on Germany on September 3. Soviet troops invade Poland. World War II begins.

image September 1, George C. Marshall is sworn in as Chief of Staff of the US Army. After the war, Churchill refers to Marshall (the only military leader to serve through the entirety of WW II) as the Architect of Victory for his crucial role in ensuring the defeat of the Axis Powers. The very day that Hitler launches all-out war in Europe, the man who will oversee his defeat takes command of the US Military — a military that, at the time, contained only 334,000 total personnel.

(no entry for this year)

1940

(no entry for this year)

G. W. Beadle and E. L. Tatum publish their classic study on the biochemical genetics of Neurospora and promulgate the ONE-GENE, ONE-ENZYME theory.

K. Mather coins the term polygenes and describes polygenic traits in various organisms.

1941

Between 1941 and 1945, the desperate need for labor in US defense plants and shipyards leads to the migration of 1.2 million African-Americans from the South to the North and West. This migration transforms American politics as blacks increasingly vote in their new homes and put pressure on Congress to protect civil rights throughout the nation. Their activism lays much of the foundation for the national civil rights movement a decade later.

On June 25, Pres. Franklin Roosevelt issues Executive Order 8802, which desegregates US defense plants and shipyards and creates the Fair Employment Practices Committee.

image The US Army creates the Tuskegee Air Squadron (the 99th Pursuit Squadron) — an all African-American flying unit.

image 07 DEC 1941: Pearl Harbor bombed by Japanese The US immediately declares war on Japan. Germany quickly declares war on the United States. The US is now a full participant in World War II.

image 08 DEC 1941: The US responds to Pearl Harbor. President to address joint session of Congress. Declaration of War expected.

image 09 DEC 1941: The United States formally declares War on Japan.

Ernst Mayr publishes Systematics and the Origin of Species, and Julian Huxley publishes Evolution: The Modern Synthesis. Both books are significant contributions to the neo darwinian synthesis combining elements of natural selection, genetics, mutation, population biology and paleontology.

S. E. Luria and T. F. Anderson publish the first electron micrographs of bacterial viruses. T2 has a polyhedral body and a tail.

1942

image 4-7 JUN 1942: The Battle of Midway occurs. Less than six months after Pearl Harbor the Japanese navy attempts to lure the remnants of the US Navy into a decisive battle at Midway Island. The Japanese plan backfires, as the battle proves to be a huge victory for US forces and the turning point in the war in the Pacific.

Theoretical physicist Erwin Schrödinger publishes What is Life? arguing that living organisms store and pass along information, perhaps using something like Morse code. This book will inspire James Watson, Francis Crick and Maurice Wilkins, who will share the Nobel prize for discovering the structure of DNA.

O. T. Avery, C. M. MacLeod, and M. McCarty describe the pneumococcus transforming principle. The fact that it is rich in DNA suggests that DNA and not protein is the hereditary chemical.

1944

On April 3, the United States Supreme Court in Smith vs. Allright declares white-only political primaries unconstitutional.

image D-Day landing On June 6th, the largest amphibious force ever assembled, led by General Dwight D. Eisenhower, successfully attacks and establishes a landing on the coast of France at Normandy.

image S. E. Luria demonstrates that mutations occur in bacterial viruses.

1945

image 13 APR 1945: President Roosevelt dies in office.

image Harry S. Truman becomes thirty-third president of the United States.

image 28 APR 1945: US and Russian troops meet. Germany split in two.

image 30 APR 1945: Press reports Mussolini killed by Italian partisans, his body abused. Hitler commits suicide by gunshot while hiding in his Führerbunker, but news of his death will not surface for a few days.

image 02 MAY 1945: Hitler reported dead..

image 08 MAY 1945: Germany surrenders unconditionally. The war in Europe is over.

image 22 JUN 1945: Okinawa falls after 82 days of fierce fighting.

image 16 JUL 1945: The Manhattan Project yields results — the world's first atomic bomb is secretly tested in New Mexico.

image 27 JUL 1945: Churchill is defeated in British elections. Potsdam Declaration is reported, calling for Japan to surrender unconditionally or face "prompt and utter destruction."

image 06 AUG 1945: the first atomic bomb used in combat is dropped on Hiroshima, Japan.

image 07 AUG 1945: The world learns about the atomic bomb. President Truman announces "The force from which the sun draws its power has been loosed against those who brought war to the Far East" and he calls upon Japan to immediately accept the terms of the Potsdam Declaration or expect a rain of ruin from the air, the like of which has never been seen on this earth."

image 09 AUG 1945: The second atomic bomb used in combat is dropped on Nagasaki, Japan. The primary target for this mission was actually the city of Kokura, but the bomber crew moved on to the secondary target of Nagasaki when Kokura proved to be too obscured by smoke to get a clear view for the bombsight. Russia declares war on japan.

image 15 AUG 1945: In the afternoon of August 15th (Japanese time), Japan announces its unconditional surrender. World War II is finally over. More than 60 million people have died as a result of the conflict.

image Col. Benjamin O. Davis, Jr, is named commander of Godman Field, Kentucky. He is the first African-American to command a United States military base.

1946

The United States Supreme Court, in Morgan vs Virginia, rules that segregation in interstate bus travel is unconstitutional.

(no entry for this year)

1947

image On April 10, Jackie Robinson of the Brooklyn Dodgers becomes the first African-American to play major league baseball in the 20th century.

image H. J. Muller coins the term dosage compensation.

J. Lederberg and N. Zinder, and, independently, B. D. Davis develop the penicillin selection technique for isolating biochemically deficient bacterial mutants.

1948

On July 26, Pres. Harry Truman issues Executive Order 9981, directing the desegregation of the armed forces.

The United States Supreme Court, in Shelley vs Kraemer, rules that racially restrictive covenants are legally unenforceable.

A. D. Hershey and R. Rotman demonstrate that genetic recombination occurs in bacteriophage.

J. V. Neel provides genetic evidence that the sickle-cell disease is inherited as a simple Mendelian autosomal recessive.

1949

(no entry for this year)

At a Cold Spring Harbor Symposium, Ernst Mayr argues that all hominid specimens so far found should be categorized in the genus Homo: H. transvaalensis, H. erectus, and H. sapiens.

E. Chargaff lays the foundations for nucleic acid structural studies by his analytical work. He demonstrates for DNA that the numbers of adenine and thymine groups are always equal and so are the numbers of guanine and cytosine groups. These findings later suggest to Watson and Crick that DNA consists of two polynucleotide strands joined by hydrogen bonding between A and T and between G and C.

E. M. Lederberg discovers lambda, the first viral episome of E. coli.

1950

(no entry for this year)

Barbara McClintock publishes a paper describing "jumping" genes that can move around within an organism's genome.

1951

image On May 24, a mob of 3500 whites attempt to prevent a black family from moving into an apartment in Cicero, Illinois. Illinois Gov. Adlai Stevenson calls out the Illinois National Guard to protect the family and restore order.

On May 24, the United States Supreme Court rules that racial segregation in District of Columbia restaurants is unconstitutional.

A. D. Hershey and M. Chase demonstrate that the DNA of phage enters the host, whereas most of the protein remains behind.

F. Sanger and his colleagues work out the complete amino acid sequence for the protein hormone insulin, and show that it contains two polypeptide chains held together by disulfide bridges.

J. Lederberg and E. M. Lederberg invent the replica plating technique.

N. D. Zinder and J. Lederberg describe transduction in Salmonella.

1952

(no entry for this year)

image image J. D. Watson and F. H. C. Crick propose a model for DNA comprised of two helically intertwined chains tied together by hydrogen bonds between the purines and pyrimidines.

W. Hayes discovers polarized behavior in bacterial recombinations. He isolates the Hfr H strain of E. coli and shows that certain genes are readily transferred from Hfr to F- bacteria, whereas others are not.

1953

(no entry for this year)

1954

On May 17, the United States Supreme Court, in Brown vs the Board of Education, declares segregation in all public schools in the United States unconstitutional, nullifying the earlier judicial doctrine of "separate but equal."

image S. Benzer works out the fine structure of the rII region of phage T4 of E. coli, and coins the terms CISTRON,RECON, and MUTON.

1955

image Rosa Parks refuses to relinquish her bus seat to a white man on December 1, initiating the Montgomery bus boycott. Soon afterward, Martin Luther King, Jr., becomes the leader of the boycott.

image Fourteen-year-old Chicago resident Emmett Till is lynched in Money, Mississippi, on August 28.

F. Jacob and E. L. Wollman are able experimentally to interrupt the mating process in E. coli and show that a piece of DNA is inserted from the donor bacterium into the recipient.

1956

(no entry for this year)

Francis Crick proposes the "central dogma" of genetic information transfer: DNA specifies RNA and RNA specifies cell proteins.

V. M. Ingram reports that normal and sickle-cell hemoglobin differ by a single amino acid substitution.

1957

Congress passes the Civil Rights Act of 1957, the first legislation protecting black rights since Reconstruction.

In September, Pres. Dwight D. Eisenhower sends federal troops to Little Rock, Arkansas, to ensure the enforcement of a federal court order to desegregate Central High School and to protect nine African-American students enrolled as part of the order.

Frederick Sanger receives a Nobel Prize in Chemistry for his work on the structure of proteins, especially that of insulin.

George W. Beadle, Edward L. Tatum, and Joshua Lederberg share a Nobel Prize in Medicine for Beadle and Tatum's discovery that genes act by regulating definite chemical events, and for Lederberg's discoveries concerning genetic recombination and the organization of the genetic material of bacteria.

image F. H. C. Crick suggests that during protein formation the amino acid is carried to the template by an adaptor molecule containing nucleotides and that the adaptor is the part that actually fits on the RNA template. Crick thus predicts the discovery of transfer RNA.

F. Jacob and E. L. Wollman demonstrate that the single linkage group of E. coli is circular and suggest that the different linkage groups found in different Hfr strains result from the insertion at different points of a factor in the circular linkage group that determines the rupture of the circle.

M. Meselson and F. W. Stahl use the density gradient equilibrium centrifugation technique to demonstrate the semiconservative distribution of density label during DNA replication in E. coli.

1958

(no entry for this year)

Severo Ochoa and Arthur Kornberg share a Nobel Prize in Medicine for their discovery of the mechanisms in the biological synthesis of ribonucleic acid and deoxiribonucleic acid.

J. Lejeune, M. Gautier, and R. Turpin show that Down syndrome is a chromosomal aberration involving trisomy of a small telocentric chromosome.

R. L. Sinsheimer demonstrates that bacteriophage phiX174 of E. coli contains a single-stranded DNA molecule.

1959

image The US flag is modified to have forty-nine stars, reflecting the addition of one new state: Alaska.

Alister Hardy promotes his Homo aquaticus or "aquatic ape" hypothesis to the British Sub Aqua Club. He will follow up this announcement with several magazine articles.

1960

image The US flag is modified to have fifty stars, reflecting the addition of one new state: Hawaii.

The Civil Rights Act of 1960 is signed into law by Pres. Dwight D. Eisenhower on May 6. The act establishes federal inspection of local voter registration rolls and introduces penalties for anyone who obstructs a citizens attempt to register to vote or to cast a ballot.

image image F. Jacob and J. Monod publish "Genetic regulatory mechanisms in the synthesis of proteins," a paper in which the theory of the OPERON is developed.

1961

The Congress of Racial Equality organizes Freedom Rides through the Deep South.

image John F. Kennedy becomes thirty-fifth president of the United States.

Human geneticist James Neel develops the "thrifty genotype" hypothesis that human ancestors endured feast-famine cycles that made the human body very effective in storing fat for lean times.

image image image James Watson, Francis Crick, and Maurice Wilkins share a Nobel Prize in Medicine for their work in elucidating the structure of DNA.

1962

image On October 1, James Meredith becomes the first black student to enroll at the University of Mississippi.

(no entry for this year)

1963

Martin Luther King Jr. writes his "Letter from Birmingham Jail" on April 16.

Kennedy assassinated.

Lyndon Johnson becomes thirty-sixth president of the United States.

image Martin Luther King Jr. is named Time magazine's Man of the Year.

image On June 12, Mississippi NAACP field secretary Medgar Evers is assassinated outside his home in Jackson.

(no entry for this year)

1964

Congress passes the Civil Rights Act of 1964. The act and this discrimination in all public accommodations and by employers. It also establishes the Equal Opportunity Employment Commission (EEOC) to monitor compliance with the law.

image image image On June 21, civil rights workers James Chaney, Andrew Goodman, and Michael Schwerner are abducted and killed by terrorists in Mississippi.

The 24th amendment to the Constitution, which abolishes the poll tax, is ratified.

1965

image Malcolm X is assassinated at the Audubon Ballroom in Harlem on February 21.

The Watts Uprising occurs on August 11-16th. Thirty-four people are killed and 1000 are injured in the five-day confrontation.

Willi Hennig works on a new approach to assessing evolutionary relationships, known as cladistics. Although it will be hotly debated, this technique will eventually become standard practice in paleontology, botany and zoology.

1966

image On June 5, James Meredith begins a solitary March Against Fear for 220 miles from Memphis, Tennessee, to Jackson, Mississippi, to protest racial discrimination. Meredith is shot by a sniper soon after crossing into Mississippi.

image On November 8, Edward Brooke of Massachusetts becomes the first African-American to be elected to the United States Senate since Reconstruction.

image image On September 15, the Black Panther Party is formed in Oakland, California, by Bobby Seale and Huey P. Newton.

Lynn Sagan (later Lynn Margulis) hypothesizes that chloroplasts originated as cyanobacteria, and that mitochondria originated as bacteria. She suggests that both were engulfed by other cells and began functioning as symbionts.

1967

image On July 13, Thurgood Marshall takes his seat as the first African-American justice on the United States Supreme Court.

On June 12, the United States Supreme Court, in Loving vs Virginia, strikes down state interracial marriage bans.

The six-day Newark Riot begins on July 12.

A.G. Cairns-Smith publishes a paper suggesting that the first life on Earth might have been fine-grained clay crystals. He will publish on this topic several more times before his death, but the experimental evidence will remain scant, perhaps in part because sufficient technology doesn't yet exist to test the hypothesis.

Robert W. Holley, Har Gobind Khorana, and Marshall W. Nirenberg share a Nobel Prize in Medicine for their interpretation of the genetic code and its function in protein synthesis.

1968

image On April 4, Martin Luther King, Jr., is assassinated in Memphis, Tennessee. In the wake of the assassination, 125 cities in 29 states experience uprisings.

image On June 5, New York Senator and presidential candidate Robert F. Kennedy is assassinated in Los Angeles.

(no entry for this year)

1970

image Dr. Clifton Wharton Junior is named president of Michigan State University on January 2. He is the first African-American to lead a major, predominantly white university in the 20th century.

Five pairs of adult wall lizards are moved between two islands in Croatia. Over the next few decades, the lizards on the new island will evolve larger heads, stronger bites, and a greater tolerance for an herbivorous diet than the original lizard population.

1971

On January 12, the Congressional Black Caucus is formed in Washington DC.

1972

image image In November, Barbara Jordan of Houston and Andrew Young of Atlanta become the first black Congressional representatives elected from the US South since 1898.

Half in jest, Francis Crick and Leslie Orgel suggest that ancient aliens may have seeded the early Earth with DNA, and all life on this planet arose from that.

Peter and Rosemary Grant begin a long-term study of finches on the Galápagos Islands. In succeeding years, as they watch finches adapt to alternating wet and dry conditions, the Grants will uncover evidence that evolution proceeds more rapidly than what Darwin estimated.

Taking a line from Through the Looking Glass, Leigh Van Valen establishes the "Red Queen" hypothesis of coevolution between predator and prey: "it takes all the running you can do, to keep in the same place. If you want to get somewhere else, you must run at least twice as fast as that!"

1973

image In the late summer of 1973, Republican Vice President Spiro Agnew was under investigation by the United States Attorney's office in Baltimore, Maryland, on charges of extortion, tax fraud, bribery and conspiracy. In October, he was formally charged with having accepted bribes totaling more than $100,000, while holding office as Baltimore County Executive, Governor of Maryland, and as Vice President of the United States. On October 10, 1973, Agnew was allowed to plead no contest to a single charge that he had failed to report $29,500 of income received in 1967, with the condition that he resign the office of Vice President. Agnew is the only Vice President in U.S. history to resign because of criminal charges.

image Thomas Bradley is elected the first black mayor of Los Angeles in the modern era. He is reelected four times and thus holds the mayor's office for 20 years.

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1974

image Under mounting impeachment pressure resulting from the Watergate break-in, Nixon becomes the first president ever to resign from presidency.

image Gerald Ford becomes thirty-eighth president of the United States.

Mary-Claire King and Allan Wilson publish their finding that human and chimpanzee DNA sequences differ by roughly 1 percent, meaning humans have more in common with chimps than chimps do with gorillas. King and Wilson suggest that humans and chimps differ largely in the DNA that switches on and off genes.

David Baltimore, Renato Dulbecco, and Howard Temin share Nobel Prize in Medicine for their discoveries concerning the interaction between tumour viruses and the genetic material of the cell.

1975

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Overturning the classifications introduced by R. H. Whittaker seven years earlier, Carl Woese proposes to divide all living things into three categories: Bacteria, Archaea and Eukarya.

1976

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Submersible vehicle Alvin reveals deep sea vents on the ocean floor that give rise to an ecosystem owing nothing to photosynthesis. This finding prompts speculation that life on Earth first arose in deep-sea, not shallow-water, ecosystems.

Fred Sanger and collaborators publish the first complete DNA sequence of an organism, a bacteriophage, or virus infecting bacteria.

1977

image The eighth and final night for the televised miniseries based on Alex Haley's Roots is shown on February 3. This final episode achieves the highest ratings to that point for a single television program.

Jimmy Carter becomes thirty-ninth president of the United States.

image Fresh out of law school and short on cash, Robert Heggestad buys an antique cabinet on an installment plan from a Virginia antique shop. The cabinet turns out to contain some 1,700 plant and invertebrate specimens from the personal collection of Alfred Russel Wallace.

1979

image On March 28, a partial core meltdown occurred in Unit 2 of the Three Mile Island Nuclear Generating Station in Dauphin County, Pennsylvania near Harrisburg.

Christiane Nüsslein-Volhard and Eric Wieschaus describe genetic mutations affecting the body plan of the fruit fly Drosophila, and identify genes controlling the basic body plans of all animals. These genes will eventually be known as Hox genes.

Paul Berg, Walter Gilbert, and Frederick Sanger share a Nobel Prize in Chemistry, with Berg cited for his fundamental studies of the biochemistry of nucleic acids, with particular regard to recombinant-DNA, and Gilbert and Sanger cited for their contributions concerning the determination of base sequences in nucleic acids. This is Sanger's second Nobel, the first having come in 1958 for his work on the structure of insulin.

1980

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1982

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1983

On November 2, Pres. Ronald Reagan signs into law a bill making the third Monday in January a federal holiday honoring the life of Martin Luther King Jr.

David Raup and Jack Sepkoski publish the controversial claim that mass extinctions are regularly spaced at 26 million years.

1984

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1985

United States Rep. William H. Gray III (Pennsylvania), becomes the first African-American congressmen to chair the House Budget Committee.

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1986

On September 8, The Oprah Winfrey Show from Chicago becomes nationally syndicated.

image On April 26, the Chernobyl Nuclear Disaster occurred in the Soviet Union, when reactor 4 of the Chernobyl Nuclear Power Plant suffered a catastrophic power increase, leading to explosions in the core. This dispersed large quantities of radioactive fuel and core materials into the atmosphere and ignited the combustible graphite moderator. The burning graphite moderator increased the emission of radioactive particles, carried by the smoke, as the reactor had not been contained by any kind of hard containment vessel (unlike all Western plants). The accident occurred during an experiment scheduled to test a potential safety emergency core cooling feature. Large areas in Ukraine, Belarus, and Russia had to be evacuated, with over 336,000 people resettled.

Allan Wilson and Rebecca Cann announce that all humans share a common ancestor who lived in Africa as recently as 150,000 years ago. Because the discovery is based on examination of mitochondrial DNA, the ancestral entity will be given the popular (and somewhat misleading) name of "Mitochondrial Eve." The controversial finding will be supported by another discovery in 2000.

1987

image Dr. Clifton R. Wharton Jr. is appointed chairman and CEO of TIAA-CREF, the 19th largest US Fortune 500 company. He becomes the first black chairman and CEO of a major US corporation.

image Kurt Schmoke becomes the first African-American elected mayor of Baltimore.

Molecular biologist John Cairns describes experiments suggesting that bacteria facing environmental stress can "direct" their mutations to produce favorable adaptations. Directed mutation will remain a controversial idea, but the possibility that organisms mutate at a greater rate (hypermutation) under environmental stress will gain more acceptance.

1988

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1989

image Douglas Wilder wins the governorship of Virginia, make him the first African-American to be popularly elected to that office.

image Gen. Colin L. Powell is named chief of the United States Joint Chiefs of Staff, the first African-American in the youngest person (52) to hold the post.

image In March, Frederick Andrew Gregory becomes the first African-American to command a space shuttle when he leads the crew of the Discovery.

George Bush becomes forty-first president of the United States.

The Human Genome Project is launched with the goal of sequencing all 3 billion base pairs of human DNA by 2005.

1990

image Nelson Mandela, South African black nationalist, is freed after 27 years in prison.

Chicxulub crater is discovered in the Yucatán Peninsula, supporting the asteroid impact theory first suggested in 1980.

1991

The Soviet Union ends, and so does the Cold War.

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1992

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1994

image On April 27, Nelson Mandela is elected President of South Africa in that nation's first election giving black voters full enfranchisement. The land of apartheid is now led by a black activist.

Using "molecular clock" estimates of mutation rates, Greg Wray and collaborators hypothesize that metazoan phyla diverged from each other 1 billion years ago, or even earlier. In other words, they argue that metazoans existed hundreds of millions of years before the earliest metazoan fossils (about 600 million years old) yet found.

1996

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1997

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1998

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1999

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Based on studies of Y chromosomes, Peter Underhill publishes his finding that all modern humans share a common ancestor, bolstering the 1987 announcement from Cann and Wilson. This suggests a "bottleneck" event (population crash) among human ancestors living in Africa roughly 150,000 years ago.

Sally McBearty and Alison Brooks publish "The Revolution that Wasn't" challenging the long-held notion of a "big bang" in human intellectual evolution approximately 40,000 years ago. Instead, they cite evidence for earlier appearances of modern behavior.

2000

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image Alfred Sturtevant's A History of Genetics is republished jointly by the Electronic Scholarly Publishing Project and the Cold Spring Harbor Laboratory Press. Sturtevant provides an insider's perspective (he created the FIRST GENETIC MAP ) to this first-rate summary of the foundations of classical genetics.

CLICK TO BUY THIS BOOK

The International Human Genome Sequencing Consortium (Human Genome Project) publishes the initial sequence and analysis of the human genome in Nature Magazine. Celera Genomics simultaneously publishes a draft human genome sequence in Science Magazine.

Leland H. Hartwell, R. Timothy Hunt, and Sir Paul M. Nurse share a Nobel Prize in Medicine for their discoveries of key regulators of the cell cycle.

2001

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2003

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Peter Brown, Mike Morwood and collaborators announce the find of a 1-meter- tall hominid skeleton on the Indonesian island of Flores. Found near the remains of giant lizards and pygmy elephants, the new species is formally named Homo floresiensis and nicknamed the "hobbit." Though some suspect it's a kind of malformed, small-brained midget, this interpretation will be answered by braincase scans, wrist bones too primitive to be Homo sapiens, and the announcement of several more individuals of the same species. Later studies will suggest direct ancestry from Homo erectus, although another study will argue the remains really indicate Down syndrome. The species is initially given an estimated age as young as 11,000 years, but later research will indicate an age of at least 50,000 years.

2004

Barack Obama is elected to the United States Senate from Illinois. He becomes the second African-American elected to the Senate from that state, and only the fifth black US senator in history.

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2005

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Jean Moliner, Gerhard Ries, Cyril Zipfel and Barbara Hohn publish their findings on stressed plants that not only mutate at a greater rate, but also pass an increased mutation tendency to their offspring.

Andrew Z. Fine and Craig C. Mello share a Nobel Prize in Medicine for their discovery of RNA interference — gene silencing by double-stranded RNA.

Roger D. Kornberg was awarded a Nobel Prize in Chemistry for his studies of the molecular basis of eukaryotic transcription.

2006

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After studying grunting fish, Andrew Bass and colleagues report that the part of the brain controlling volcalization is extremely primitive, and propose that vertebrates evolved the ability to communicate through sound some 400 million years ago.

2008

On August 27, Illinois Sen. Barack Obama becomes the first African-American to attain the Democratic Party nomination for president of the United States when he is chosen at the party's national convention in Denver.

Ryan Kerney announces the discovery of algae (Oophila amblystomatis) living inside spotted salamander (Ambystoma maculatum) embryo cells — the first discovery of a photosynthetic symbiont living inside vertebrate cells.

Candy makers Hershey and Mars finance competing genomic sequences for cacao (the primary ingredient of chocolate).

Robert G. Edwards receives the Nobel prize in Medicine "for the development of in vitro fertilization"

2010

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Two studies released in the same week indicate that modern Melanesians and Aboriginal Australians descended from an earlier migration out of Africa than did other populations. Further, the studies suggest that participants in the earlier migration interbred with Denisovans.

Bruce A. Beutler and Jules A. Hoffmann share the Nobel Prize in Medicine "for their discoveries concerning the activation of innate immunity"

2011

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Based on new genetic research, David Reich, Svante Pääbo and collaborators announce at a Royal Society of London meeting that Denisovans bred with Neanderthals, ancestors of people now living in East Asia and Oceania, and another group of extinct archaic humans who were genetically dissimilar to both Neanderthals and modern humans. A few weeks later, Matthias Meyer, Svante Pääbo and coauthors describe the oldest hominin DNA sequence to date, from a 400,000-year-old femur from Spain's Sima de los Huesos. The mitochondrial DNA indicate an unexpected link to Denisovans.

Using genetic material from more than 300 individuals, including aboriginal Australians from the Northern Territory, a team of geneticists argues that Australians — long believed isolated from other populations for some 45,000 years — received substantial gene flow from India about 4,230 years ago.

James E. Rothman, Randy W. Schekman and Thomas C. Südhof share the Nobel Prize in Medicine "for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells"

2013

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Bhart-Anjan Bhullar, Arhat Abzhanov and colleagues announce that they have reverse engineered dinosaur snouts in chicken embryos by altering beak- building gene expressions.

Stephen Hackley publishes a review article arguing that human brains retain vestigial neural circuitry, the same circuitry that currently allows other mammals (and once allowed our ancient ancestors) to orient their ears toward novel stimuli.

William C. Campbell and Satoshi Omura share the Nobel prize in Medicine "for their discoveries concerning a novel therapy against infections caused by roundworm parasites" and Tu Youyou receives a Nobel {rize in Medicine "for her discoveries concerning a novel therapy against Malaria"

2015

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2019

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2020

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2021

image Joe Biden becomes the 46th President of the United States.

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2022

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2023

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2024

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2025

image Donald Trump becomes the 47th President of the United States, with Republican majorities in the Senate and House and with a Supreme Court packed with his picks (and likely more on the way). A strong wind blows to the right.

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2026

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2027

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2028

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2029

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ESP Quick Facts

ESP Origins

In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.

ESP Support

In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.

ESP Rationale

Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.

ESP Goal

In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.

ESP Usage

Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.

ESP Content

When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.

ESP Help

Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.

ESP Plans

With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.

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Timeline

The new, dynamic Timeline from the Electronic Scholarly Publishing Project gives users more control over the timeline display.

We seek your suggestions for timeline content, both for individual events and for entire subjects.

To submit a correction or a recommendation or to propose new Timeline content (or to volunteer as a Timeline Editor), click HERE.

The Electronic Scholarly Publishing Project needs help: with acquiring content, with writing, with editing, with graphic production, and with financial support.

CLICK HERE to see what ESP needs most.

ESP Picks from Around the Web (updated 06 MAR 2017 )