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ESP: PubMed Auto Bibliography 07 Oct 2024 at 01:46 Created:
Drosophila: The Fly Room
In the small "Fly Room" at Columbia University, T. H. Morgan and his students, A. H. Sturtevant, C. B. Bridges, H. J. Muller, carried out the work that laid the foundations of modern, chromosomal genetics. The excitement of those times, when the whole field of genetics was being created, is captured in this book, written by one of those present at the beginning. In a time when genomics and genetics maps are discussed almost daily in the popular press, it is worth remembering that the world's first genetic map was created in 1913 by A. H. Sturtevant, then a sophomore in college. In 1933, Morgan received the Nobel Prize in medicine, for his "discoveries concerning the role played by the chro- mosome in heredity." In the 67 years since, genetics has continued to advance, leaving behind a fascinating history. The year 2000 was the 100th anniversary of the founding of modern genetics with the rediscovery of Mendel' work and it is the year in which the full DNA sequence of the Drosophila genome was obtained. The fruit fly is still at the center of genetic research, just as it was in 1910 when work first began in Morgan's fly room.
Created with PubMed® Query: ( 1890:1932[PDAT] AND (drosophila OR gene OR genetic OR map OR chromosome OR mutant OR mutation) AND ( "morgan th"[author] OR "morgan lv"[author] OR "sturtevant AH"[author] OR "bridges CB"[author] OR "muller HJ"[author] ) ) NOT pmcbook NOT ispreviousversion
Citations The Papers (from PubMed®)
RevDate: 2010-06-10
CmpDate: 2010-07-02
THE RISE OF GENETICS. II.
Science (New York, N.Y.), 76(1970):285-288.
Additional Links: PMID-17754102
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@article {pmid17754102,
year = {1932},
author = {Morgan, TH},
title = {THE RISE OF GENETICS. II.},
journal = {Science (New York, N.Y.)},
volume = {76},
number = {1970},
pages = {285-288},
doi = {10.1126/science.76.1970.285},
pmid = {17754102},
issn = {0036-8075},
}
RevDate: 2010-06-10
CmpDate: 2010-07-02
THE RISE OF GENETICS.
Science (New York, N.Y.), 76(1969):261-267.
Additional Links: PMID-17840456
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PubMed:
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@article {pmid17840456,
year = {1932},
author = {Morgan, TH},
title = {THE RISE OF GENETICS.},
journal = {Science (New York, N.Y.)},
volume = {76},
number = {1969},
pages = {261-267},
doi = {10.1126/science.76.1969.261},
pmid = {17840456},
issn = {0036-8075},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Linkage Relations of Certain Genes in Oenothera.
Genetics, 17(4):393-412.
Additional Links: PMID-17246659
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@article {pmid17246659,
year = {1932},
author = {Emerson, S and Sturtevant, AH},
title = {The Linkage Relations of Certain Genes in Oenothera.},
journal = {Genetics},
volume = {17},
number = {4},
pages = {393-412},
pmid = {17246659},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
The Inadequacy of the Sub-Gene Hypothesis of the Nature of the Scute Allelomorphs of Drosophila.
Proceedings of the National Academy of Sciences of the United States of America, 17(5):265-270.
Additional Links: PMID-16577357
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@article {pmid16577357,
year = {1931},
author = {Sturtevant, AH and Schultz, J},
title = {The Inadequacy of the Sub-Gene Hypothesis of the Nature of the Scute Allelomorphs of Drosophila.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {17},
number = {5},
pages = {265-270},
doi = {10.1073/pnas.17.5.265},
pmid = {16577357},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Are "Progressive" Mutations Produced by X-Rays?.
Genetics, 15(6):495-577.
Additional Links: PMID-17246607
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@article {pmid17246607,
year = {1930},
author = {Patterson, JT and Muller, HJ},
title = {Are "Progressive" Mutations Produced by X-Rays?.},
journal = {Genetics},
volume = {15},
number = {6},
pages = {495-577},
pmid = {17246607},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
RECIPROCAL TRANSLOCATIONS IN DROSOPHILA AND THEIR BEARING ON OENOTHERA CYTOLOGY AND GENETICS.
Proceedings of the National Academy of Sciences of the United States of America, 16(8):533-536.
Additional Links: PMID-16587601
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@article {pmid16587601,
year = {1930},
author = {Sturtevant, AH and Dobzhansky, T},
title = {RECIPROCAL TRANSLOCATIONS IN DROSOPHILA AND THEIR BEARING ON OENOTHERA CYTOLOGY AND GENETICS.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {16},
number = {8},
pages = {533-536},
pmid = {16587601},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Frequency of Translocations Produced by X-Rays in Drosophila.
Genetics, 15(4):283-311.
Additional Links: PMID-17246601
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@article {pmid17246601,
year = {1930},
author = {Muller, HJ and Altenburg, E},
title = {The Frequency of Translocations Produced by X-Rays in Drosophila.},
journal = {Genetics},
volume = {15},
number = {4},
pages = {283-311},
pmid = {17246601},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
EVIDENCE THAT NATURAL RADIOACTIVITY IS INADEQUATE TO EXPLAIN THE FREQUENCY OF "NATURAL" MUTATIONS.
Proceedings of the National Academy of Sciences of the United States of America, 16(4):277-285.
Additional Links: PMID-16587566
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@article {pmid16587566,
year = {1930},
author = {Muller, HJ and Mott-Smith, LM},
title = {EVIDENCE THAT NATURAL RADIOACTIVITY IS INADEQUATE TO EXPLAIN THE FREQUENCY OF "NATURAL" MUTATIONS.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {16},
number = {4},
pages = {277-285},
pmid = {16587566},
issn = {0027-8424},
}
RevDate: 2010-06-10
CmpDate: 2010-07-02
SOME PHYSICOCHEMICAL ASPECTS OF LIFE, MUTATION AND EVOLUTION.
Science (New York, N.Y.), 70(1821):508-510.
Additional Links: PMID-17759789
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@article {pmid17759789,
year = {1929},
author = {Alexander, J and Bridges, CB},
title = {SOME PHYSICOCHEMICAL ASPECTS OF LIFE, MUTATION AND EVOLUTION.},
journal = {Science (New York, N.Y.)},
volume = {70},
number = {1821},
pages = {508-510},
doi = {10.1126/science.70.1821.508},
pmid = {17759789},
issn = {0036-8075},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
A Further Study of the so-Called Mutation at the Bar Locus of Drosophila.
Genetics, 13(5):401-409.
Additional Links: PMID-17246556
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@article {pmid17246556,
year = {1928},
author = {Sturtevant, AH},
title = {A Further Study of the so-Called Mutation at the Bar Locus of Drosophila.},
journal = {Genetics},
volume = {13},
number = {5},
pages = {401-409},
doi = {10.1093/genetics/13.5.401},
pmid = {17246556},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
The Production of Mutations by X-Rays.
Proceedings of the National Academy of Sciences of the United States of America, 14(9):714-726.
Additional Links: PMID-16587397
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@article {pmid16587397,
year = {1928},
author = {Muller, HJ},
title = {The Production of Mutations by X-Rays.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {14},
number = {9},
pages = {714-726},
pmid = {16587397},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Measurement of Gene Mutation Rate in Drosophila, Its High Variability, and Its Dependence upon Temperature.
Genetics, 13(4):279-357.
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@article {pmid17246553,
year = {1928},
author = {Muller, HJ},
title = {The Measurement of Gene Mutation Rate in Drosophila, Its High Variability, and Its Dependence upon Temperature.},
journal = {Genetics},
volume = {13},
number = {4},
pages = {279-357},
pmid = {17246553},
issn = {0016-6731},
}
RevDate: 2022-03-21
CmpDate: 2010-07-02
ARTIFICIAL TRANSMUTATION OF THE GENE.
Science (New York, N.Y.), 66(1699):84-87.
Additional Links: PMID-17802387
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@article {pmid17802387,
year = {1927},
author = {Muller, HJ},
title = {ARTIFICIAL TRANSMUTATION OF THE GENE.},
journal = {Science (New York, N.Y.)},
volume = {66},
number = {1699},
pages = {84-87},
doi = {10.1126/science.66.1699.84},
pmid = {17802387},
issn = {0036-8075},
}
RevDate: 2021-10-20
CmpDate: 2010-06-23
THE RELATION OF THE AGE OF THE FEMALE TO CROSSING OVER IN THE THIRD CHROMOSOME OF DROSOPHILA MELANOGASTER.
The Journal of general physiology, 8(6):689-700.
The four methods of examining the relation of amount of multiple crossing over to age of mothers agree in showing that the "internode length" or average distance required for double crossing over has changed in a characteristic fashion, giving an M-shaped curve. These changes have not been independent of changes in total recombination but concomitant with them. However, the changes in recombination percentages were far greater than could be accounted for by change in internode length, and the larger factor must be assumed to be changes in the coefficients of crossing over. The amounts of these changes are greatest for the mid-sections of the chromosome and least for the distal sections. The changes in the two limbs are of like amount for equal distances from the center of symmetry in the distribution of simple and multiple crossing over.
Additional Links: PMID-19872223
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@article {pmid19872223,
year = {1927},
author = {Bridges, CB},
title = {THE RELATION OF THE AGE OF THE FEMALE TO CROSSING OVER IN THE THIRD CHROMOSOME OF DROSOPHILA MELANOGASTER.},
journal = {The Journal of general physiology},
volume = {8},
number = {6},
pages = {689-700},
doi = {10.1085/jgp.8.6.689},
pmid = {19872223},
issn = {0022-1295},
abstract = {The four methods of examining the relation of amount of multiple crossing over to age of mothers agree in showing that the "internode length" or average distance required for double crossing over has changed in a characteristic fashion, giving an M-shaped curve. These changes have not been independent of changes in total recombination but concomitant with them. However, the changes in recombination percentages were far greater than could be accounted for by change in internode length, and the larger factor must be assumed to be changes in the coefficients of crossing over. The amounts of these changes are greatest for the mid-sections of the chromosome and least for the distal sections. The changes in the two limbs are of like amount for equal distances from the center of symmetry in the distribution of simple and multiple crossing over.},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Mutants of the Extreme Left End of the Second Chromosome of DROSOPHILA MELANOGASTER.
Genetics, 11(6):503-530.
Additional Links: PMID-17246469
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@article {pmid17246469,
year = {1926},
author = {Stern, C and Bridges, CB},
title = {The Mutants of the Extreme Left End of the Second Chromosome of DROSOPHILA MELANOGASTER.},
journal = {Genetics},
volume = {11},
number = {6},
pages = {503-530},
pmid = {17246469},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Linkage Relations of a Benign Tumor in Drosophila.
Genetics, 11(3):249-266.
Additional Links: PMID-17246453
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@article {pmid17246453,
year = {1926},
author = {Stark, MB and Bridges, CB},
title = {The Linkage Relations of a Benign Tumor in Drosophila.},
journal = {Genetics},
volume = {11},
number = {3},
pages = {249-266},
doi = {10.1093/genetics/11.3.249},
pmid = {17246453},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Correlation between Shape and Behavior of a Chromosome.
Proceedings of the National Academy of Sciences of the United States of America, 12(3):180-181.
Additional Links: PMID-16576974
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@article {pmid16576974,
year = {1926},
author = {Morgan, LV},
title = {Correlation between Shape and Behavior of a Chromosome.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {12},
number = {3},
pages = {180-181},
doi = {10.1073/pnas.12.3.180},
pmid = {16576974},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Multiple Stock "Xple" and Its Use.
Genetics, 11(1):41-56.
Additional Links: PMID-17246444
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@article {pmid17246444,
year = {1926},
author = {Bridges, CB and Olbrycht, TM},
title = {The Multiple Stock "Xple" and Its Use.},
journal = {Genetics},
volume = {11},
number = {1},
pages = {41-56},
doi = {10.1093/genetics/11.1.41},
pmid = {17246444},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Standard Errors of Chromosome Distances and Coincidence.
Genetics, 10(6):509-524.
Additional Links: PMID-17246287
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@article {pmid17246287,
year = {1925},
author = {Muller, HJ and Jacobs-Muller, JM},
title = {The Standard Errors of Chromosome Distances and Coincidence.},
journal = {Genetics},
volume = {10},
number = {6},
pages = {509-524},
doi = {10.1093/genetics/10.6.509},
pmid = {17246287},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Haploidy in Drosophila Melanogaster.
Proceedings of the National Academy of Sciences of the United States of America, 11(11):706-710.
Additional Links: PMID-16576932
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@article {pmid16576932,
year = {1925},
author = {Bridges, CB},
title = {Haploidy in Drosophila Melanogaster.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {11},
number = {11},
pages = {706-710},
doi = {10.1073/pnas.11.11.706},
pmid = {16576932},
issn = {0027-8424},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Elimination of Chromosomes Due to a Mutant (Minute-N) in Drosophila Melanogaster.
Proceedings of the National Academy of Sciences of the United States of America, 11(11):701-706.
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@article {pmid16576931,
year = {1925},
author = {Bridges, CB},
title = {Elimination of Chromosomes Due to a Mutant (Minute-N) in Drosophila Melanogaster.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {11},
number = {11},
pages = {701-706},
doi = {10.1073/pnas.11.11.701},
pmid = {16576931},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Regionally Differential Effect of X Rays on Crossing over in Autosomes of Drosophila.
Genetics, 10(5):470-507.
Additional Links: PMID-17246286
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@article {pmid17246286,
year = {1925},
author = {Muller, HJ},
title = {The Regionally Differential Effect of X Rays on Crossing over in Autosomes of Drosophila.},
journal = {Genetics},
volume = {10},
number = {5},
pages = {470-507},
pmid = {17246286},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Crossing over in the X Chromosomes of Triploid Females of DROSOPHILA MELANOGASTER.
Genetics, 10(5):418-441.
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@article {pmid17246283,
year = {1925},
author = {Bridges, CB and Anderson, EG},
title = {Crossing over in the X Chromosomes of Triploid Females of DROSOPHILA MELANOGASTER.},
journal = {Genetics},
volume = {10},
number = {5},
pages = {418-441},
pmid = {17246283},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Polyploidy in DROSOPHILA MELANOGASTER with Two Attached X Chromosomes.
Genetics, 10(2):148-178.
Additional Links: PMID-17246267
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@article {pmid17246267,
year = {1925},
author = {Morgan, LV},
title = {Polyploidy in DROSOPHILA MELANOGASTER with Two Attached X Chromosomes.},
journal = {Genetics},
volume = {10},
number = {2},
pages = {148-178},
doi = {10.1093/genetics/10.2.148},
pmid = {17246267},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Effects of Unequal Crossing over at the Bar Locus in Drosophila.
Genetics, 10(2):117-147.
Additional Links: PMID-17246266
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@article {pmid17246266,
year = {1925},
author = {Sturtevant, AH},
title = {The Effects of Unequal Crossing over at the Bar Locus in Drosophila.},
journal = {Genetics},
volume = {10},
number = {2},
pages = {117-147},
pmid = {17246266},
issn = {0016-6731},
}
RevDate: 2010-06-10
CmpDate: 2010-07-02
REVERSE MUTATION OF THE BAR GENE CORRELATED WITH CROSSING OVER.
Science (New York, N.Y.), 57(1487):746-747.
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@article {pmid17788502,
year = {1923},
author = {Sturtevant, AH and Morgan, TH},
title = {REVERSE MUTATION OF THE BAR GENE CORRELATED WITH CROSSING OVER.},
journal = {Science (New York, N.Y.)},
volume = {57},
number = {1487},
pages = {746-747},
doi = {10.1126/science.57.1487.746},
pmid = {17788502},
issn = {0036-8075},
}
RevDate: 2010-06-10
CmpDate: 2010-07-02
TRIPLOID INTERSEXES IN DROSOPHILA MELANOGASTER.
Science (New York, N.Y.), 54(1394):252-254.
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@article {pmid17769897,
year = {1921},
author = {Bridges, CB},
title = {TRIPLOID INTERSEXES IN DROSOPHILA MELANOGASTER.},
journal = {Science (New York, N.Y.)},
volume = {54},
number = {1394},
pages = {252-254},
doi = {10.1126/science.54.1394.252},
pmid = {17769897},
issn = {0036-8075},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
A Case of Rearrangement of Genes in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America, 7(8):235-237.
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@article {pmid16576597,
year = {1921},
author = {Sturtevant, AH},
title = {A Case of Rearrangement of Genes in Drosophila.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {7},
number = {8},
pages = {235-237},
pmid = {16576597},
issn = {0027-8424},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Genetical and Cytological Proof of Non-disjunction of the Fourth Chromosome of Drosophila Melanogaster.
Proceedings of the National Academy of Sciences of the United States of America, 7(7):186-192.
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@article {pmid16586837,
year = {1921},
author = {Bridges, CB},
title = {Genetical and Cytological Proof of Non-disjunction of the Fourth Chromosome of Drosophila Melanogaster.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {7},
number = {7},
pages = {186-192},
pmid = {16586837},
issn = {0027-8424},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Linkage Variation and Chromosome Maps.
Proceedings of the National Academy of Sciences of the United States of America, 7(7):181-183.
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@article {pmid16586834,
year = {1921},
author = {Sturtevant, AH},
title = {Linkage Variation and Chromosome Maps.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {7},
number = {7},
pages = {181-183},
pmid = {16586834},
issn = {0027-8424},
}
RevDate: 2010-06-10
CmpDate: 2010-07-02
PROOF OF NON-DISJUNCTION FOR THE FOURTH CHROMOSOME OF DROSOPHILA MELANOGASTER.
Science (New York, N.Y.), 53(1370):308.
Additional Links: PMID-17784143
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@article {pmid17784143,
year = {1921},
author = {Bridges, CB},
title = {PROOF OF NON-DISJUNCTION FOR THE FOURTH CHROMOSOME OF DROSOPHILA MELANOGASTER.},
journal = {Science (New York, N.Y.)},
volume = {53},
number = {1370},
pages = {308},
doi = {10.1126/science.53.1370.308},
pmid = {17784143},
issn = {0036-8075},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Current Maps of the Location of the Mutant Genes of Drosophila Melanogaster.
Proceedings of the National Academy of Sciences of the United States of America, 7(4):127-132.
Additional Links: PMID-16576592
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@article {pmid16576592,
year = {1921},
author = {Bridges, CB},
title = {Current Maps of the Location of the Mutant Genes of Drosophila Melanogaster.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {7},
number = {4},
pages = {127-132},
doi = {10.1073/pnas.7.4.127},
pmid = {16576592},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Genetic Studies on DROSOPHILA SIMULANS. III. Autosomal Genes. General Discussion.
Genetics, 6(2):179-207.
Additional Links: PMID-17245963
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@article {pmid17245963,
year = {1921},
author = {Sturtevant, AH},
title = {Genetic Studies on DROSOPHILA SIMULANS. III. Autosomal Genes. General Discussion.},
journal = {Genetics},
volume = {6},
number = {2},
pages = {179-207},
pmid = {17245963},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Genetic Studies on DROSOPHILA SIMULANS. II. Sex-Linked Group of Genes.
Genetics, 6(1):43-64.
Additional Links: PMID-17245955
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Citation:
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@article {pmid17245955,
year = {1921},
author = {Sturtevant, AH},
title = {Genetic Studies on DROSOPHILA SIMULANS. II. Sex-Linked Group of Genes.},
journal = {Genetics},
volume = {6},
number = {1},
pages = {43-64},
pmid = {17245955},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
The Mutant Crossveinless in Drosophila Melanogaster.
Proceedings of the National Academy of Sciences of the United States of America, 6(11):660-663.
Additional Links: PMID-16576553
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@article {pmid16576553,
year = {1920},
author = {Bridges, CB},
title = {The Mutant Crossveinless in Drosophila Melanogaster.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {6},
number = {11},
pages = {660-663},
doi = {10.1073/pnas.6.11.660},
pmid = {16576553},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Genetic Studies on DROSOPHILA SIMULANS. I. Introduction. Hybrids with DROSOPHILA MELANOGASTER.
Genetics, 5(5):488-500.
Additional Links: PMID-17245951
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@article {pmid17245951,
year = {1920},
author = {Sturtevant, AH},
title = {Genetic Studies on DROSOPHILA SIMULANS. I. Introduction. Hybrids with DROSOPHILA MELANOGASTER.},
journal = {Genetics},
volume = {5},
number = {5},
pages = {488-500},
doi = {10.1093/genetics/5.5.488},
pmid = {17245951},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
The Evidence for the Linear Order of the Genes.
Proceedings of the National Academy of Sciences of the United States of America, 6(4):162-164.
Additional Links: PMID-16576482
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@article {pmid16576482,
year = {1920},
author = {Morgan, TH and Sturtevant, AH and Bridge, CB},
title = {The Evidence for the Linear Order of the Genes.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {6},
number = {4},
pages = {162-164},
doi = {10.1073/pnas.6.4.162},
pmid = {16576482},
issn = {0027-8424},
}
RevDate: 2010-06-10
CmpDate: 2010-07-02
INTERSEXES IN DROSOPHILA SIMULANS.
Science (New York, N.Y.), 51(1317):325-327.
Additional Links: PMID-17773838
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PubMed:
Citation:
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@article {pmid17773838,
year = {1920},
author = {Sturtevant, AH},
title = {INTERSEXES IN DROSOPHILA SIMULANS.},
journal = {Science (New York, N.Y.)},
volume = {51},
number = {1317},
pages = {325-327},
doi = {10.1126/science.51.1317.325},
pmid = {17773838},
issn = {0036-8075},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Genetic Basis of Truncate Wing,-an Inconstant and Modifiable Character in Drosophila.
Genetics, 5(1):1-59.
Additional Links: PMID-17245940
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@article {pmid17245940,
year = {1920},
author = {Altenburg, E and Muller, HJ},
title = {The Genetic Basis of Truncate Wing,-an Inconstant and Modifiable Character in Drosophila.},
journal = {Genetics},
volume = {5},
number = {1},
pages = {1-59},
doi = {10.1093/genetics/5.1.1},
pmid = {17245940},
issn = {0016-6731},
}
RevDate: 2021-10-20
CmpDate: 2010-06-22
VERMILION-DEFICIENCY.
The Journal of general physiology, 1(6):645-656.
In May, 1916, a culture of Drosophila melanogaster showed that a new sex-linked lethal had arisen. The linkage relations indicated that the position of the lethal was in the neighborhood of the sex-linked recessive "vermilion," whose locus in the X chromosome is at 33.0. When females heterozygous for the lethal were outcrossed to vermilion males, all the daughters that received the lethal-bearing chromosome showed vermilion eye-color, though, from the pedigree, vermilion was known to be absent from the ancestry of the mother. The lethal action and the unexpected appearance of vermilion both suggested that this was another instance of the phenomenon called "deficiency;" that is, the loss or "inactivation" of the genes of a section of the X chromosome. The lethal action would then be due to the deficient region including one or more genes necessary for the life of the individual. The appearance of vermilion in females carrying only one vermilion gene would be explainable on the ground that the deficient-bearing females are virtually haploid for the region including the vermilion locus. Linkage tests showed that the amount of crossing over in the neighborhood of the deficiency was cut down by about five units. Part of this may be attributed to the actual length of the "deficient" region, within which it is probable that no crossing over occurs, and part (probably most) to an alteration in the synaptic relations in the regions immediately adjacent. In more remote regions there was no disturbance or perhaps a slight rise in the frequency of crossing over. Both the local fall and the possible rise in more distant regions would seem to argue that a "pucker" at synapsis had been caused by an actual shortening of the deficient chromosome. That the deficient region extends to the left of the locus of vermilion was indicated by a test in which it was observed that the presence of an extra piece of chromosome including the loci for vermilion and sable ("vermilion-sable duplication") did not neutralize the lethal action of the deficiency. Haploid tests with the other recessive mutations in the neighborhood of vermilion showed that the deficiency was not extensive enough to include their loci. Cytological preparations were made but were unsatisfactory. The stock was finally lost, apparently as the result of injurious action upon viability, fertility, and productivity by the deficiency.
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Citation:
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@article {pmid19871779,
year = {1919},
author = {Bridges, CB},
title = {VERMILION-DEFICIENCY.},
journal = {The Journal of general physiology},
volume = {1},
number = {6},
pages = {645-656},
pmid = {19871779},
issn = {0022-1295},
abstract = {In May, 1916, a culture of Drosophila melanogaster showed that a new sex-linked lethal had arisen. The linkage relations indicated that the position of the lethal was in the neighborhood of the sex-linked recessive "vermilion," whose locus in the X chromosome is at 33.0. When females heterozygous for the lethal were outcrossed to vermilion males, all the daughters that received the lethal-bearing chromosome showed vermilion eye-color, though, from the pedigree, vermilion was known to be absent from the ancestry of the mother. The lethal action and the unexpected appearance of vermilion both suggested that this was another instance of the phenomenon called "deficiency;" that is, the loss or "inactivation" of the genes of a section of the X chromosome. The lethal action would then be due to the deficient region including one or more genes necessary for the life of the individual. The appearance of vermilion in females carrying only one vermilion gene would be explainable on the ground that the deficient-bearing females are virtually haploid for the region including the vermilion locus. Linkage tests showed that the amount of crossing over in the neighborhood of the deficiency was cut down by about five units. Part of this may be attributed to the actual length of the "deficient" region, within which it is probable that no crossing over occurs, and part (probably most) to an alteration in the synaptic relations in the regions immediately adjacent. In more remote regions there was no disturbance or perhaps a slight rise in the frequency of crossing over. Both the local fall and the possible rise in more distant regions would seem to argue that a "pucker" at synapsis had been caused by an actual shortening of the deficient chromosome. That the deficient region extends to the left of the locus of vermilion was indicated by a test in which it was observed that the presence of an extra piece of chromosome including the loci for vermilion and sable ("vermilion-sable duplication") did not neutralize the lethal action of the deficiency. Haploid tests with the other recessive mutations in the neighborhood of vermilion showed that the deficiency was not extensive enough to include their loci. Cytological preparations were made but were unsatisfactory. The stock was finally lost, apparently as the result of injurious action upon viability, fertility, and productivity by the deficiency.},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
The Inheritance of the Mutant Character "Vortex".
Genetics, 4(3):283-306.
Additional Links: PMID-17245927
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@article {pmid17245927,
year = {1919},
author = {Bridges, CB and Mohr, OL},
title = {The Inheritance of the Mutant Character "Vortex".},
journal = {Genetics},
volume = {4},
number = {3},
pages = {283-306},
doi = {10.1093/genetics/4.3.283},
pmid = {17245927},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
The Spatial Relations of Genes.
Proceedings of the National Academy of Sciences of the United States of America, 5(5):168-173.
Additional Links: PMID-16576369
PubMed:
Citation:
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@article {pmid16576369,
year = {1919},
author = {Sturtevant, AH and Bridges, CB and Morgan, TH},
title = {The Spatial Relations of Genes.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {5},
number = {5},
pages = {168-173},
pmid = {16576369},
issn = {0027-8424},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Maroon: A Recurrent Mutation in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America, 4(10):316-318.
Additional Links: PMID-16576317
PubMed:
Citation:
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@article {pmid16576317,
year = {1918},
author = {Bridges, CB},
title = {Maroon: A Recurrent Mutation in Drosophila.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {4},
number = {10},
pages = {316-318},
pmid = {16576317},
issn = {0027-8424},
}
RevDate: 2021-10-20
CmpDate: 2010-06-22
LUTEAR CELLS AND HEN-FEATHERING.
The Journal of general physiology, 1(1):127-131.
The experimental evidence had made clear that some substance is produced in the testis of the male Sebright that suppresses in him the development of the secondary sexual plumage of the cock of his species. The detection in his testis of lutear cells like those in hens makes the conclusion highly probable that it is these cells that cause the suppression of cock-feathering in both the Sebright male and in hens of all fowls. Genetic work by Morgan had shown that one or two Mendelian factor-differences are responsible for hen-feathering in the Sebright. These factor-differences produce their effects through the testes. The presence of these genetic factors, we now see, causes the testes of the Sebright to produce a kind of secretory cell that is ordinarily only produced in the female, or possibly to a slight extent in young males (Boring), or in numbers insufficient to suppress the male plumage in the testes of some ordinary cock birds (Reeves).
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@article {pmid19871722,
year = {1918},
author = {Boring, AM and Morgan, TH},
title = {LUTEAR CELLS AND HEN-FEATHERING.},
journal = {The Journal of general physiology},
volume = {1},
number = {1},
pages = {127-131},
doi = {10.1085/jgp.1.1.127},
pmid = {19871722},
issn = {0022-1295},
abstract = {The experimental evidence had made clear that some substance is produced in the testis of the male Sebright that suppresses in him the development of the secondary sexual plumage of the cock of his species. The detection in his testis of lutear cells like those in hens makes the conclusion highly probable that it is these cells that cause the suppression of cock-feathering in both the Sebright male and in hens of all fowls. Genetic work by Morgan had shown that one or two Mendelian factor-differences are responsible for hen-feathering in the Sebright. These factor-differences produce their effects through the testes. The presence of these genetic factors, we now see, causes the testes of the Sebright to produce a kind of secretory cell that is ordinarily only produced in the female, or possibly to a slight extent in young males (Boring), or in numbers insufficient to suppress the male plumage in the testes of some ordinary cock birds (Reeves).},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Genetic Variability, Twin Hybrids and Constant Hybrids, in a Case of Balanced Lethal Factors.
Genetics, 3(5):422-499.
Additional Links: PMID-17245914
PubMed:
Citation:
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@article {pmid17245914,
year = {1918},
author = {Muller, HJ},
title = {Genetic Variability, Twin Hybrids and Constant Hybrids, in a Case of Balanced Lethal Factors.},
journal = {Genetics},
volume = {3},
number = {5},
pages = {422-499},
pmid = {17245914},
issn = {0016-6731},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
A PARALLEL MUTATION IN DROSOPHILA FUNEBRIS.
Science (New York, N.Y.), 48(1229):72-73.
Additional Links: PMID-17818909
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PubMed:
Citation:
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@article {pmid17818909,
year = {1918},
author = {Sturtevant, AH},
title = {A PARALLEL MUTATION IN DROSOPHILA FUNEBRIS.},
journal = {Science (New York, N.Y.)},
volume = {48},
number = {1229},
pages = {72-73},
doi = {10.1126/science.48.1229.72},
pmid = {17818909},
issn = {0036-8075},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Incompatibility of Mutant Races in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America, 3(12):673-678.
Additional Links: PMID-16586764
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@article {pmid16586764,
year = {1917},
author = {Metz, CW and Bridges, CB},
title = {Incompatibility of Mutant Races in Drosophila.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {3},
number = {12},
pages = {673-678},
pmid = {16586764},
issn = {0027-8424},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
An Oenothera-Like Case in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America, 3(10):619-626.
Additional Links: PMID-16586762
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@article {pmid16586762,
year = {1917},
author = {Muller, HJ},
title = {An Oenothera-Like Case in Drosophila.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {3},
number = {10},
pages = {619-626},
doi = {10.1073/pnas.3.10.619},
pmid = {16586762},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Deficiency.
Genetics, 2(5):445-465.
Additional Links: PMID-17245891
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@article {pmid17245891,
year = {1917},
author = {Bridges, CB},
title = {Deficiency.},
journal = {Genetics},
volume = {2},
number = {5},
pages = {445-465},
doi = {10.1093/genetics/2.5.445},
pmid = {17245891},
issn = {0016-6731},
}
RevDate: 2019-05-01
CmpDate: 2006-06-01
Genetic Factors Affecting the Strength of Linkage in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America, 3(9):555-558.
Additional Links: PMID-16586749
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Citation:
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@article {pmid16586749,
year = {1917},
author = {Sturtevant, AH},
title = {Genetic Factors Affecting the Strength of Linkage in Drosophila.},
journal = {Proceedings of the National Academy of Sciences of the United States of America},
volume = {3},
number = {9},
pages = {555-558},
pmid = {16586749},
issn = {0027-8424},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Crossing over without Chiasmatype?.
Genetics, 2(3):301-304.
Additional Links: PMID-17245885
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@article {pmid17245885,
year = {1917},
author = {Sturtevant, AH},
title = {Crossing over without Chiasmatype?.},
journal = {Genetics},
volume = {2},
number = {3},
pages = {301-304},
doi = {10.1093/genetics/2.3.301},
pmid = {17245885},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Non-Disjunction as Proof of the Chromosome Theory of Heredity (Concluded).
Genetics, 1(2):107-163.
Additional Links: PMID-17245853
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@article {pmid17245853,
year = {1916},
author = {Bridges, CB},
title = {Non-Disjunction as Proof of the Chromosome Theory of Heredity (Concluded).},
journal = {Genetics},
volume = {1},
number = {2},
pages = {107-163},
doi = {10.1093/genetics/1.2.107},
pmid = {17245853},
issn = {0016-6731},
}
RevDate: 2021-09-16
CmpDate: 2007-02-02
Non-Disjunction as Proof of the Chromosome Theory of Heredity.
Genetics, 1(1):1-52.
Additional Links: PMID-17245850
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@article {pmid17245850,
year = {1916},
author = {Bridges, CB},
title = {Non-Disjunction as Proof of the Chromosome Theory of Heredity.},
journal = {Genetics},
volume = {1},
number = {1},
pages = {1-52},
doi = {10.1093/genetics/1.1.1},
pmid = {17245850},
issn = {0016-6731},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
DIRECT PROOF THROUGH NON-DISJUNCTION THAT THE SEX-LINKED GENES OF DROSOPHILA ARE BORNE BY THE X-CHROMOSOME.
Science (New York, N.Y.), 40(1020):107-109.
Additional Links: PMID-17807969
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PubMed:
Citation:
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@article {pmid17807969,
year = {1914},
author = {Bridges, CB},
title = {DIRECT PROOF THROUGH NON-DISJUNCTION THAT THE SEX-LINKED GENES OF DROSOPHILA ARE BORNE BY THE X-CHROMOSOME.},
journal = {Science (New York, N.Y.)},
volume = {40},
number = {1020},
pages = {107-109},
doi = {10.1126/science.40.1020.107},
pmid = {17807969},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
A FACTOR FOR THE FOURTH CHROMOSOME OF DROSOPHILA.
Science (New York, N.Y.), 39(1016):906.
Additional Links: PMID-17796754
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@article {pmid17796754,
year = {1914},
author = {Muller, HJ},
title = {A FACTOR FOR THE FOURTH CHROMOSOME OF DROSOPHILA.},
journal = {Science (New York, N.Y.)},
volume = {39},
number = {1016},
pages = {906},
doi = {10.1126/science.39.1016.906-a},
pmid = {17796754},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
HAS THE WHITE MAN MORE CHROMOSOMES THAN THE NEGRO?.
Science (New York, N.Y.), 39(1014):827-828.
Additional Links: PMID-17821329
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PubMed:
Citation:
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@article {pmid17821329,
year = {1914},
author = {Morgan, TH},
title = {HAS THE WHITE MAN MORE CHROMOSOMES THAN THE NEGRO?.},
journal = {Science (New York, N.Y.)},
volume = {39},
number = {1014},
pages = {827-828},
doi = {10.1126/science.39.1014.827},
pmid = {17821329},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
A THIRD GROUP OF LINKED GENES IN DROSOPHILA AMPELOPHILA.
Science (New York, N.Y.), 37(965):990-992.
Additional Links: PMID-17833164
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Citation:
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@article {pmid17833164,
year = {1913},
author = {Sturtevant, AH},
title = {A THIRD GROUP OF LINKED GENES IN DROSOPHILA AMPELOPHILA.},
journal = {Science (New York, N.Y.)},
volume = {37},
number = {965},
pages = {990-992},
doi = {10.1126/science.37.965.990},
pmid = {17833164},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
CHROMOSOMES AND ASSOCIATIVE INHERITANCE.
Science (New York, N.Y.), 34(880):636-638.
Additional Links: PMID-17817201
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PubMed:
Citation:
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@article {pmid17817201,
year = {1911},
author = {Morgan, TH},
title = {CHROMOSOMES AND ASSOCIATIVE INHERITANCE.},
journal = {Science (New York, N.Y.)},
volume = {34},
number = {880},
pages = {636-638},
doi = {10.1126/science.34.880.636},
pmid = {17817201},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
THE ORIGIN OF FIVE MUTATIONS IN EYE COLOR IN DROSOPHILA AND THEIR MODES OF INHERITANCE.
Science (New York, N.Y.), 33(849):534-537.
Additional Links: PMID-17817675
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PubMed:
Citation:
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hide bibtex listing
@article {pmid17817675,
year = {1911},
author = {Morgan, TH},
title = {THE ORIGIN OF FIVE MUTATIONS IN EYE COLOR IN DROSOPHILA AND THEIR MODES OF INHERITANCE.},
journal = {Science (New York, N.Y.)},
volume = {33},
number = {849},
pages = {534-537},
doi = {10.1126/science.33.849.534-a},
pmid = {17817675},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
THE ORIGIN OF NINE WING MUTATIONS IN DROSOPHILA.
Science (New York, N.Y.), 33(848):496-499.
Additional Links: PMID-17774436
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PubMed:
Citation:
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hide bibtex listing
@article {pmid17774436,
year = {1911},
author = {Morgan, TH},
title = {THE ORIGIN OF NINE WING MUTATIONS IN DROSOPHILA.},
journal = {Science (New York, N.Y.)},
volume = {33},
number = {848},
pages = {496-499},
doi = {10.1126/science.33.848.496},
pmid = {17774436},
issn = {0036-8075},
}
RevDate: 2010-06-09
CmpDate: 2010-07-02
SEX LIMITED INHERITANCE IN DROSOPHILA.
Science (New York, N.Y.), 32(812):120-122.
Additional Links: PMID-17759620
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PubMed:
Citation:
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@article {pmid17759620,
year = {1910},
author = {Morgan, TH},
title = {SEX LIMITED INHERITANCE IN DROSOPHILA.},
journal = {Science (New York, N.Y.)},
volume = {32},
number = {812},
pages = {120-122},
doi = {10.1126/science.32.812.120},
pmid = {17759620},
issn = {0036-8075},
}
ESP Quick Facts
ESP Origins
In the early 1990's, Robert Robbins was a faculty member at Johns Hopkins, where he directed the informatics core of GDB — the human gene-mapping database of the international human genome project. To share papers with colleagues around the world, he set up a small paper-sharing section on his personal web page. This small project evolved into The Electronic Scholarly Publishing Project.
ESP Support
In 1995, Robbins became the VP/IT of the Fred Hutchinson Cancer Research Center in Seattle, WA. Soon after arriving in Seattle, Robbins secured funding, through the ELSI component of the US Human Genome Project, to create the original ESP.ORG web site, with the formal goal of providing free, world-wide access to the literature of classical genetics.
ESP Rationale
Although the methods of molecular biology can seem almost magical to the uninitiated, the original techniques of classical genetics are readily appreciated by one and all: cross individuals that differ in some inherited trait, collect all of the progeny, score their attributes, and propose mechanisms to explain the patterns of inheritance observed.
ESP Goal
In reading the early works of classical genetics, one is drawn, almost inexorably, into ever more complex models, until molecular explanations begin to seem both necessary and natural. At that point, the tools for understanding genome research are at hand. Assisting readers reach this point was the original goal of The Electronic Scholarly Publishing Project.
ESP Usage
Usage of the site grew rapidly and has remained high. Faculty began to use the site for their assigned readings. Other on-line publishers, ranging from The New York Times to Nature referenced ESP materials in their own publications. Nobel laureates (e.g., Joshua Lederberg) regularly used the site and even wrote to suggest changes and improvements.
ESP Content
When the site began, no journals were making their early content available in digital format. As a result, ESP was obliged to digitize classic literature before it could be made available. For many important papers — such as Mendel's original paper or the first genetic map — ESP had to produce entirely new typeset versions of the works, if they were to be available in a high-quality format.
ESP Help
Early support from the DOE component of the Human Genome Project was critically important for getting the ESP project on a firm foundation. Since that funding ended (nearly 20 years ago), the project has been operated as a purely volunteer effort. Anyone wishing to assist in these efforts should send an email to Robbins.
ESP Plans
With the development of methods for adding typeset side notes to PDF files, the ESP project now plans to add annotated versions of some classical papers to its holdings. We also plan to add new reference and pedagogical material. We have already started providing regularly updated, comprehensive bibliographies to the ESP.ORG site.
ESP Picks from Around the Web (updated 28 JUL 2024 )
Old Science
Weird Science
Treating Disease with Fecal Transplantation
Fossils of miniature humans (hobbits) discovered in Indonesia
Paleontology
Dinosaur tail, complete with feathers, found preserved in amber.
Astronomy
Mysterious fast radio burst (FRB) detected in the distant universe.
Big Data & Informatics
Big Data: Buzzword or Big Deal?
Hacking the genome: Identifying anonymized human subjects using publicly available data.
